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- NCIT_C47437 IAO_0000115 "The disodium salt form of cefotetan and a semi-synthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefotetan disodium causes inhibition of bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. This results in a reduction of cell wall stability and causes cell lysis." @default.
- NCIT_C47437 NCIT_A6 NCIT_C61664 @default.
- NCIT_C47437 NCIT_NHC0 "C47437" @default.
- NCIT_C47437 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47437 NCIT_P108 "Cefotetan Disodium" @default.
- NCIT_C47437 NCIT_P207 "C0007553" @default.
- NCIT_C47437 NCIT_P210 "74356-00-6" @default.
- NCIT_C47437 NCIT_P319 "0GXP746VXB" @default.
- NCIT_C47437 NCIT_P322 "FDA" @default.
- NCIT_C47437 NCIT_P350 "C17H15N7O8S4.2Na" @default.
- NCIT_C47437 NCIT_P366 "Cefotetan_Disodium" @default.
- NCIT_C47437 NCIT_P368 "CHEBI:34617" @default.
- NCIT_C47437 normalizedInformationContent "100" @default.
- NCIT_C47437 referenceCount "1" @default.
- NCIT_C47437 hasExactSynonym "5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl)carbonyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, Disodium Salt,(6R-(6alpha,7alpha))-" @default.
- NCIT_C47437 hasExactSynonym "CEFOTETAN DISODIUM" @default.
- NCIT_C47437 hasExactSynonym "Cefotan" @default.
- NCIT_C47437 hasExactSynonym "Cefotetan Disodium" @default.
- NCIT_C47437 hasExactSynonym "Ceftenon" @default.
- NCIT_C47437 hasExactSynonym "Cepan" @default.
- NCIT_C47437 hasExactSynonym "Darvilen" @default.
- NCIT_C47437 hasExactSynonym "YM-09330" @default.
- NCIT_C47437 inSubset NCIT_C63923 @default.
- NCIT_C47437 type Class @default.
- NCIT_C47437 isDefinedBy ncit.owl @default.
- NCIT_C47437 label "Cefotetan Disodium" @default.
- NCIT_C47437 subClassOf NCIT_C1908 @default.
- NCIT_C47437 subClassOf NCIT_C1909 @default.
- NCIT_C47437 subClassOf NCIT_C254 @default.
- NCIT_C47437 subClassOf NCIT_C258 @default.
- NCIT_C47437 subClassOf NCIT_C260 @default.
- NCIT_C47437 subClassOf NCIT_C357 @default.
- NCIT_C47437 subClassOf NCIT_C47437 @default.