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- NCIT_C47493 IAO_0000115 "A malate salt of diltazem, a benzothiazepine calcium channel blocking agent. Diltiazem inhibits the transmembrane influx of extracellular calcium ions into select myocardial and vascular smooth muscle cells, causing dilatation of coronary and systemic arteries and decreasing myocardial contractility. Because of its vasodilatory activity, this agent has been shown to improve the microcirculation in some tumors, thereby potentially improving the delivery of antineoplastic agents to tumor cells." @default.
- NCIT_C47493 NCIT_A6 NCIT_C61725 @default.
- NCIT_C47493 NCIT_NHC0 "C47493" @default.
- NCIT_C47493 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47493 NCIT_P108 "Diltiazem Malate" @default.
- NCIT_C47493 NCIT_P207 "C1165286" @default.
- NCIT_C47493 NCIT_P210 "144604-00-2" @default.
- NCIT_C47493 NCIT_P319 "14Y6444DRP" @default.
- NCIT_C47493 NCIT_P322 "FDA" @default.
- NCIT_C47493 NCIT_P350 "C22H26N2O4S.C4H6O5" @default.
- NCIT_C47493 NCIT_P366 "Diltiazem_Malate" @default.
- NCIT_C47493 normalizedInformationContent "100" @default.
- NCIT_C47493 referenceCount "1" @default.
- NCIT_C47493 hasExactSynonym "1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(di-methylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-(2S-cis)-,(S)-hydoxybutanedioate(1:1)" @default.
- NCIT_C47493 hasExactSynonym "DILTIAZEM MALATE" @default.
- NCIT_C47493 hasExactSynonym "Diltiazem Malate" @default.
- NCIT_C47493 hasExactSynonym "Tiamate" @default.
- NCIT_C47493 inSubset NCIT_C63923 @default.
- NCIT_C47493 type Class @default.
- NCIT_C47493 isDefinedBy ncit.owl @default.
- NCIT_C47493 label "Diltiazem Malate" @default.
- NCIT_C47493 subClassOf NCIT_C1908 @default.
- NCIT_C47493 subClassOf NCIT_C1909 @default.
- NCIT_C47493 subClassOf NCIT_C270 @default.
- NCIT_C47493 subClassOf NCIT_C333 @default.
- NCIT_C47493 subClassOf NCIT_C47493 @default.
- NCIT_C47493 subClassOf NCIT_C78274 @default.
- NCIT_C47493 subClassOf NCIT_C93038 @default.