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- NCIT_C47496 IAO_0000115 "A semi-synthetic macrolide antibiotic pro-drug. Dirithromycin is converted by hydrolysis during intestinal absorption into the microbiologically active erythromycylamine. Eryhtromylamine binds to the 50 S subunit of the 70 S ribosome of susceptible organisms, thereby inhibiting bacterial RNA-dependent protein synthesis. This antibiotic is used in the treatment of infections of the respiratory tract, skin and soft tissue caused by gram-positive microorganisms, including S. aureus, S. pneumonia and pyogenes, gram-negative microorganisms, including H. influenzae, L. pneumophila, M. catarrhalis, and M. pneumoniae." @default.
- NCIT_C47496 NCIT_NHC0 "C47496" @default.
- NCIT_C47496 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47496 NCIT_P108 "Dirithromycin" @default.
- NCIT_C47496 NCIT_P207 "C0058445" @default.
- NCIT_C47496 NCIT_P210 "62013-04-1" @default.
- NCIT_C47496 NCIT_P319 "1801D76STL" @default.
- NCIT_C47496 NCIT_P322 "FDA" @default.
- NCIT_C47496 NCIT_P350 "C42H78N2O14" @default.
- NCIT_C47496 NCIT_P366 "Dirithromycin" @default.
- NCIT_C47496 NCIT_P368 "CHEBI:474014" @default.
- NCIT_C47496 normalizedInformationContent "100" @default.
- NCIT_C47496 referenceCount "1" @default.
- NCIT_C47496 hasExactSynonym "DIRITHROMYCIN" @default.
- NCIT_C47496 hasExactSynonym "Dirithromycin" @default.
- NCIT_C47496 hasExactSynonym "Dynabac" @default.
- NCIT_C47496 hasExactSynonym "Erythromycin, 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethylidene)oxy)-,(9S(R))-" @default.
- NCIT_C47496 inSubset NCIT_C63923 @default.
- NCIT_C47496 type Class @default.
- NCIT_C47496 isDefinedBy ncit.owl @default.
- NCIT_C47496 label "Dirithromycin" @default.
- NCIT_C47496 subClassOf NCIT_C1908 @default.
- NCIT_C47496 subClassOf NCIT_C1909 @default.
- NCIT_C47496 subClassOf NCIT_C254 @default.
- NCIT_C47496 subClassOf NCIT_C258 @default.
- NCIT_C47496 subClassOf NCIT_C261 @default.
- NCIT_C47496 subClassOf NCIT_C47496 @default.
- NCIT_C47496 subClassOf NCIT_C784 @default.