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- NCIT_C47509 IAO_0000115 "A synthetic fluoro derivative of thiacytidine with potent antiviral activity. Emtricitabine is phosphorylated to form emtricitabine 5'-triphosphate within the cell. This metabolite inhibits the activity of human immunodeficiency virus (HIV) reverse transcriptase both by competing with the natural substrate deoxycytidine 5'-triphosphate and by incorporation into viral DNA causing a termination of DNA chain elongation (due to the lack of the essential 3'-OH group)." @default.
- NCIT_C47509 NCIT_NHC0 "C47509" @default.
- NCIT_C47509 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47509 NCIT_P107 "Emtricitabine" @default.
- NCIT_C47509 NCIT_P108 "Emtricitabine" @default.
- NCIT_C47509 NCIT_P207 "C0909839" @default.
- NCIT_C47509 NCIT_P210 "143491-57-0" @default.
- NCIT_C47509 NCIT_P319 "G70B4ETF4S" @default.
- NCIT_C47509 NCIT_P322 "CTRP" @default.
- NCIT_C47509 NCIT_P322 "FDA" @default.
- NCIT_C47509 NCIT_P329 "540668" @default.
- NCIT_C47509 NCIT_P330 "540668" @default.
- NCIT_C47509 NCIT_P350 "C8H10FN3O3S" @default.
- NCIT_C47509 NCIT_P366 "Emtricitabine" @default.
- NCIT_C47509 NCIT_P368 "CHEBI:31536" @default.
- NCIT_C47509 NCIT_P399 "540668" @default.
- NCIT_C47509 normalizedInformationContent "100" @default.
- NCIT_C47509 referenceCount "1" @default.
- NCIT_C47509 hasExactSynonym "(-)-2'-Deoxy-5-fluoro-3'-thiacytidine" @default.
- NCIT_C47509 hasExactSynonym "2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-,(2R-cis)-" @default.
- NCIT_C47509 hasExactSynonym "BW-524W91" @default.
- NCIT_C47509 hasExactSynonym "Coviracil" @default.
- NCIT_C47509 hasExactSynonym "EMTRICITABINE" @default.
- NCIT_C47509 hasExactSynonym "Emtricitabine" @default.
- NCIT_C47509 hasExactSynonym "Emtriva" @default.
- NCIT_C47509 hasExactSynonym "FTC" @default.
- NCIT_C47509 hasExactSynonym "dOTFC" @default.
- NCIT_C47509 inSubset NCIT_C116977 @default.
- NCIT_C47509 inSubset NCIT_C116978 @default.
- NCIT_C47509 inSubset NCIT_C173381 @default.
- NCIT_C47509 inSubset NCIT_C173383 @default.
- NCIT_C47509 inSubset NCIT_C176424 @default.
- NCIT_C47509 inSubset NCIT_C63923 @default.
- NCIT_C47509 type Class @default.
- NCIT_C47509 isDefinedBy ncit.owl @default.
- NCIT_C47509 label "Emtricitabine" @default.
- NCIT_C47509 subClassOf NCIT_C1589 @default.
- NCIT_C47509 subClassOf NCIT_C1908 @default.
- NCIT_C47509 subClassOf NCIT_C1909 @default.
- NCIT_C47509 subClassOf NCIT_C254 @default.
- NCIT_C47509 subClassOf NCIT_C281 @default.
- NCIT_C47509 subClassOf NCIT_C471 @default.
- NCIT_C47509 subClassOf NCIT_C47509 @default.
- NCIT_C47509 subClassOf NCIT_C97452 @default.