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- NCIT_C47512 IAO_0000115 "An histamine H1 receptor antagonist without sedative activity. Epinastine hydrochloride blocks the histamine H1 receptor and inhibits the release of histamine from mast cells. This prevents the typical allergic symptoms that are caused by histamine activity on capillaries, skin, mucous membranes, and on gastrointestinal and bronchial smooth muscles. Typical histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Epinastine also has affinity for the histamine H2, 5-HT2, and the alpha-1, alpha-2 adrenergic receptors." @default.
- NCIT_C47512 NCIT_A6 NCIT_C65515 @default.
- NCIT_C47512 NCIT_NHC0 "C47512" @default.
- NCIT_C47512 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47512 NCIT_P108 "Epinastine Hydrochloride" @default.
- NCIT_C47512 NCIT_P207 "C1321612" @default.
- NCIT_C47512 NCIT_P210 "108929-04-0" @default.
- NCIT_C47512 NCIT_P319 "GFM415S5XL" @default.
- NCIT_C47512 NCIT_P322 "FDA" @default.
- NCIT_C47512 NCIT_P350 "C16H15N3.HCl" @default.
- NCIT_C47512 NCIT_P366 "Epinastine_Hydrochloride" @default.
- NCIT_C47512 NCIT_P368 "CHEBI:51037" @default.
- NCIT_C47512 normalizedInformationContent "100" @default.
- NCIT_C47512 referenceCount "1" @default.
- NCIT_C47512 hasExactSynonym "9,13b-Dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepin-3-amine Hydrochloride" @default.
- NCIT_C47512 hasExactSynonym "Alesion" @default.
- NCIT_C47512 hasExactSynonym "EPINASTINE HYDROCHLORIDE" @default.
- NCIT_C47512 hasExactSynonym "Elestat" @default.
- NCIT_C47512 hasExactSynonym "Epinastine Hydrochloride" @default.
- NCIT_C47512 inSubset NCIT_C63923 @default.
- NCIT_C47512 type Class @default.
- NCIT_C47512 isDefinedBy ncit.owl @default.
- NCIT_C47512 label "Epinastine Hydrochloride" @default.
- NCIT_C47512 subClassOf NCIT_C1908 @default.
- NCIT_C47512 subClassOf NCIT_C1909 @default.
- NCIT_C47512 subClassOf NCIT_C29578 @default.
- NCIT_C47512 subClassOf NCIT_C308 @default.
- NCIT_C47512 subClassOf NCIT_C47512 @default.