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- NCIT_C47513 IAO_0000115 "A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerenone is used in the treatment of hypertension and congestive heart failure." @default.
- NCIT_C47513 NCIT_NHC0 "C47513" @default.
- NCIT_C47513 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47513 NCIT_P108 "Eplerenone" @default.
- NCIT_C47513 NCIT_P207 "C0961485" @default.
- NCIT_C47513 NCIT_P210 "107724-20-9" @default.
- NCIT_C47513 NCIT_P319 "6995V82D0B" @default.
- NCIT_C47513 NCIT_P322 "FDA" @default.
- NCIT_C47513 NCIT_P329 "741940" @default.
- NCIT_C47513 NCIT_P330 "741940" @default.
- NCIT_C47513 NCIT_P350 "C24H30O6" @default.
- NCIT_C47513 NCIT_P366 "Eplerenone" @default.
- NCIT_C47513 NCIT_P368 "CHEBI:31547" @default.
- NCIT_C47513 NCIT_P399 "741940" @default.
- NCIT_C47513 normalizedInformationContent "100" @default.
- NCIT_C47513 referenceCount "1" @default.
- NCIT_C47513 hasExactSynonym "9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, Methyl Ester" @default.
- NCIT_C47513 hasExactSynonym "EPLERENONE" @default.
- NCIT_C47513 hasExactSynonym "Eplerenone" @default.
- NCIT_C47513 hasExactSynonym "Inspra" @default.
- NCIT_C47513 inSubset NCIT_C176424 @default.
- NCIT_C47513 inSubset NCIT_C63923 @default.
- NCIT_C47513 type Class @default.
- NCIT_C47513 isDefinedBy ncit.owl @default.
- NCIT_C47513 label "Eplerenone" @default.
- NCIT_C47513 subClassOf NCIT_C1908 @default.
- NCIT_C47513 subClassOf NCIT_C1909 @default.
- NCIT_C47513 subClassOf NCIT_C1913 @default.
- NCIT_C47513 subClassOf NCIT_C270 @default.
- NCIT_C47513 subClassOf NCIT_C47513 @default.
- NCIT_C47513 subClassOf NCIT_C616 @default.
- NCIT_C47513 subClassOf NCIT_C718 @default.
- NCIT_C47513 subClassOf NCIT_C78274 @default.
- NCIT_C47513 subClassOf NCIT_C843 @default.