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- NCIT_C47530 IAO_0000115 "A propanediol compound with anticonvulsant and antiepileptic properties. Although the exact mechanism of action is unknown, Felbamate may be an antagonist at the strychnine-insensitive glycine-recognition site of the N-methyl-D-aspartate (NMDA) receptor-ionophore complex, thereby blocking the effects of the excitatory amino acids, suppressing neuronal firing, and preventing seizure activity. Felbamate also has weak inhibitory effects on gamma-aminobutyric acid (GABA) receptor binding sites which may contribute to its inhibitory effect on neuronal excitatory." @default.
- NCIT_C47530 NCIT_NHC0 "C47530" @default.
- NCIT_C47530 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47530 NCIT_P108 "Felbamate" @default.
- NCIT_C47530 NCIT_P207 "C0060135" @default.
- NCIT_C47530 NCIT_P210 "25451-15-4" @default.
- NCIT_C47530 NCIT_P319 "X72RBB02N8" @default.
- NCIT_C47530 NCIT_P322 "FDA" @default.
- NCIT_C47530 NCIT_P350 "C11H14N2O4" @default.
- NCIT_C47530 NCIT_P366 "Felbamate" @default.
- NCIT_C47530 NCIT_P368 "CHEBI:4995" @default.
- NCIT_C47530 normalizedInformationContent "100" @default.
- NCIT_C47530 referenceCount "1" @default.
- NCIT_C47530 hasExactSynonym "2-Phenyl-1,3-propanediol Dicarbamate" @default.
- NCIT_C47530 hasExactSynonym "Carbamic Acid, 2-phenyltrimethylene Ester" @default.
- NCIT_C47530 hasExactSynonym "FELBAMATE" @default.
- NCIT_C47530 hasExactSynonym "Felbamate" @default.
- NCIT_C47530 hasExactSynonym "Felbatol" @default.
- NCIT_C47530 inSubset NCIT_C63923 @default.
- NCIT_C47530 type Class @default.
- NCIT_C47530 isDefinedBy ncit.owl @default.
- NCIT_C47530 label "Felbamate" @default.
- NCIT_C47530 subClassOf NCIT_C1908 @default.
- NCIT_C47530 subClassOf NCIT_C1909 @default.
- NCIT_C47530 subClassOf NCIT_C264 @default.
- NCIT_C47530 subClassOf NCIT_C47530 @default.
- NCIT_C47530 subClassOf NCIT_C78272 @default.