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- NCIT_C47581 IAO_0000115 "A pyrrolidine with antiepileptic activity. The exact mechanism through which levetiracetam exerts its effects is unknown but does not involve inhibitory and excitatory neurotransmitter activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity." @default.
- NCIT_C47581 NCIT_A32 NCIT_C1909 @default.
- NCIT_C47581 NCIT_NHC0 "C47581" @default.
- NCIT_C47581 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47581 NCIT_P108 "Levetiracetam" @default.
- NCIT_C47581 NCIT_P207 "C0377265" @default.
- NCIT_C47581 NCIT_P210 "102767-28-2" @default.
- NCIT_C47581 NCIT_P302 "Treating partial-onset seizures in patients with epilepsy." @default.
- NCIT_C47581 NCIT_P319 "44YRR34555" @default.
- NCIT_C47581 NCIT_P322 "FDA" @default.
- NCIT_C47581 NCIT_P322 "GDC" @default.
- NCIT_C47581 NCIT_P325 "A drug used to treat seizures (involuntary muscle movements) caused by epilepsy (a group of brain disorders). Keppra is being studied in the treatment of seizures in patients with cancer that has spread to the brain. It is a type of anticonvulsant." @default.
- NCIT_C47581 NCIT_P329 "526173" @default.
- NCIT_C47581 NCIT_P330 "526173" @default.
- NCIT_C47581 NCIT_P350 "C8H14N2O2" @default.
- NCIT_C47581 NCIT_P366 "Levetiracetam" @default.
- NCIT_C47581 NCIT_P368 "CHEBI:6437" @default.
- NCIT_C47581 NCIT_P375 "Levetiracetam" @default.
- NCIT_C47581 NCIT_P399 "526173" @default.
- NCIT_C47581 normalizedInformationContent "100" @default.
- NCIT_C47581 referenceCount "1" @default.
- NCIT_C47581 hasExactSynonym "(S)-alpha-Ethyl-2-oxo-1-pyrrolidineacetamide" @default.
- NCIT_C47581 hasExactSynonym "1-Pyrrolidineacetamide, Alpha-ethyl-2-oxo-,(S)-" @default.
- NCIT_C47581 hasExactSynonym "Keppra" @default.
- NCIT_C47581 hasExactSynonym "LEVETIRACETAM" @default.
- NCIT_C47581 hasExactSynonym "Levetiracetam" @default.
- NCIT_C47581 hasExactSynonym "levetiracetam" @default.
- NCIT_C47581 inSubset NCIT_C157711 @default.
- NCIT_C47581 inSubset NCIT_C157712 @default.
- NCIT_C47581 inSubset NCIT_C176424 @default.
- NCIT_C47581 inSubset NCIT_C177537 @default.
- NCIT_C47581 inSubset NCIT_C63923 @default.
- NCIT_C47581 type Class @default.
- NCIT_C47581 isDefinedBy ncit.owl @default.
- NCIT_C47581 label "Levetiracetam" @default.
- NCIT_C47581 subClassOf NCIT_C1509 @default.
- NCIT_C47581 subClassOf NCIT_C1908 @default.
- NCIT_C47581 subClassOf NCIT_C1909 @default.
- NCIT_C47581 subClassOf NCIT_C26170 @default.
- NCIT_C47581 subClassOf NCIT_C264 @default.
- NCIT_C47581 subClassOf NCIT_C47581 @default.
- NCIT_C47581 subClassOf NCIT_C78272 @default.