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- NCIT_C47599 IAO_0000115 "An anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Mefenamic acid inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid. Mefenamic acid also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation." @default.
- NCIT_C47599 NCIT_NHC0 "C47599" @default.
- NCIT_C47599 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47599 NCIT_P108 "Mefenamic Acid" @default.
- NCIT_C47599 NCIT_P171 "2242038" @default.
- NCIT_C47599 NCIT_P175 "94437" @default.
- NCIT_C47599 NCIT_P207 "C0025152" @default.
- NCIT_C47599 NCIT_P210 "61-68-7" @default.
- NCIT_C47599 NCIT_P319 "367589PJ2C" @default.
- NCIT_C47599 NCIT_P322 "FDA" @default.
- NCIT_C47599 NCIT_P350 "C15H15NO2" @default.
- NCIT_C47599 NCIT_P366 "Mefenamic_Acid" @default.
- NCIT_C47599 normalizedInformationContent "100" @default.
- NCIT_C47599 referenceCount "1" @default.
- NCIT_C47599 hasExactSynonym "2-((2,3-Dimethylphenyl)amino)benzoic Acid" @default.
- NCIT_C47599 hasExactSynonym "Anthranilic Acid, N-2,3-xylyl-" @default.
- NCIT_C47599 hasExactSynonym "MEFENAMIC ACID" @default.
- NCIT_C47599 hasExactSynonym "Mefenamic Acid" @default.
- NCIT_C47599 hasExactSynonym "Ponstel" @default.
- NCIT_C47599 inSubset NCIT_C63923 @default.
- NCIT_C47599 type Class @default.
- NCIT_C47599 isDefinedBy ncit.owl @default.
- NCIT_C47599 label "Mefenamic Acid" @default.
- NCIT_C47599 subClassOf NCIT_C1908 @default.
- NCIT_C47599 subClassOf NCIT_C1909 @default.
- NCIT_C47599 subClassOf NCIT_C2198 @default.
- NCIT_C47599 subClassOf NCIT_C2356 @default.
- NCIT_C47599 subClassOf NCIT_C241 @default.
- NCIT_C47599 subClassOf NCIT_C257 @default.
- NCIT_C47599 subClassOf NCIT_C47599 @default.
- NCIT_C47599 subClassOf NCIT_C78272 @default.