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- NCIT_C47613 IAO_0000115 "A succinimide with anticonvulsant properties. Although the exact mechanism of action of methsuximide is unclear, it is thought to increase the seizure threshold and suppress the paroxysmal three-cycle-per-second spike-and-wave pattern seen with absence (petit mal) seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex and elevation of the threshold of the CNS to convulsive stimuli, probably due to direct modification of membrane function in excitable cells and/or alteration of chemically mediated neurotransmission." @default.
- NCIT_C47613 NCIT_NHC0 "C47613" @default.
- NCIT_C47613 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47613 NCIT_P108 "Methsuximide" @default.
- NCIT_C47613 NCIT_P207 "C0109002" @default.
- NCIT_C47613 NCIT_P210 "77-41-8" @default.
- NCIT_C47613 NCIT_P319 "0G76K8X6C0" @default.
- NCIT_C47613 NCIT_P322 "FDA" @default.
- NCIT_C47613 NCIT_P350 "C12H13NO2" @default.
- NCIT_C47613 NCIT_P366 "Methsuximide" @default.
- NCIT_C47613 normalizedInformationContent "100" @default.
- NCIT_C47613 referenceCount "1" @default.
- NCIT_C47613 hasExactSynonym "1,3-Dimethyl-3-phenyl-2,5-dioxopyrrolidine" @default.
- NCIT_C47613 hasExactSynonym "Celontin" @default.
- NCIT_C47613 hasExactSynonym "METHSUXIMIDE" @default.
- NCIT_C47613 hasExactSynonym "Methsuximide" @default.
- NCIT_C47613 hasExactSynonym "Succinimide, N,2-dimethyl-2-phenyl-" @default.
- NCIT_C47613 inSubset NCIT_C63923 @default.
- NCIT_C47613 type Class @default.
- NCIT_C47613 isDefinedBy ncit.owl @default.
- NCIT_C47613 label "Methsuximide" @default.
- NCIT_C47613 subClassOf NCIT_C1908 @default.
- NCIT_C47613 subClassOf NCIT_C1909 @default.
- NCIT_C47613 subClassOf NCIT_C264 @default.
- NCIT_C47613 subClassOf NCIT_C47613 @default.
- NCIT_C47613 subClassOf NCIT_C78272 @default.