Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C47622> ?p ?o ?g. }
Showing items 1 to 43 of
43
with 100 items per page.
- NCIT_C47622 IAO_0000115 "The hydrochloride salt of minocycline, a broad spectrum long-acting derivative of the antibiotic tetracycline, with antibacterial and anti-inflammatory activities. Minocycline binds to the bacterial 30S ribosomal subunit and interferes with the binding of tRNA to the ribosomal complex, thereby inhibiting protein translation in bacteria. In addition, minocycline inhibits the inflammatory enzyme 5-lipoxygenase (5LOX) and may impede T cell-microglia interactions; both activities may contribute to minocycline's neuroprotective effects. 5LOX catalyzes the synthesis of inflammatory mediators such as prostaglandins and leukotrienes." @default.
- NCIT_C47622 NCIT_A6 NCIT_C61849 @default.
- NCIT_C47622 NCIT_NHC0 "C47622" @default.
- NCIT_C47622 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47622 NCIT_P107 "Minocycline Hydrochloride" @default.
- NCIT_C47622 NCIT_P108 "Minocycline Hydrochloride" @default.
- NCIT_C47622 NCIT_P175 "141993" @default.
- NCIT_C47622 NCIT_P207 "C0026186" @default.
- NCIT_C47622 NCIT_P210 "13614-98-7" @default.
- NCIT_C47622 NCIT_P319 "0020414E5U" @default.
- NCIT_C47622 NCIT_P322 "CTRP" @default.
- NCIT_C47622 NCIT_P322 "FDA" @default.
- NCIT_C47622 NCIT_P329 "552699" @default.
- NCIT_C47622 NCIT_P330 "552699" @default.
- NCIT_C47622 NCIT_P350 "C23H27N3O7.HCl" @default.
- NCIT_C47622 NCIT_P366 "Minocycline_Hydrochloride" @default.
- NCIT_C47622 NCIT_P368 "CHEBI:50697" @default.
- NCIT_C47622 NCIT_P399 "552699" @default.
- NCIT_C47622 normalizedInformationContent "100" @default.
- NCIT_C47622 referenceCount "1" @default.
- NCIT_C47622 hasExactSynonym "4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride" @default.
- NCIT_C47622 hasExactSynonym "Dynacin" @default.
- NCIT_C47622 hasExactSynonym "MINOCYCLINE HYDROCHLORIDE" @default.
- NCIT_C47622 hasExactSynonym "Minocin" @default.
- NCIT_C47622 hasExactSynonym "Minocycline Hydrochloride" @default.
- NCIT_C47622 hasExactSynonym "Minomax" @default.
- NCIT_C47622 hasExactSynonym "Minomycin" @default.
- NCIT_C47622 hasExactSynonym "Tri-minocycline" @default.
- NCIT_C47622 hasExactSynonym "Vectrin" @default.
- NCIT_C47622 inSubset NCIT_C116977 @default.
- NCIT_C47622 inSubset NCIT_C116978 @default.
- NCIT_C47622 inSubset NCIT_C176424 @default.
- NCIT_C47622 inSubset NCIT_C63923 @default.
- NCIT_C47622 type Class @default.
- NCIT_C47622 isDefinedBy ncit.owl @default.
- NCIT_C47622 label "Minocycline Hydrochloride" @default.
- NCIT_C47622 subClassOf NCIT_C1595 @default.
- NCIT_C47622 subClassOf NCIT_C1908 @default.
- NCIT_C47622 subClassOf NCIT_C1909 @default.
- NCIT_C47622 subClassOf NCIT_C254 @default.
- NCIT_C47622 subClassOf NCIT_C258 @default.
- NCIT_C47622 subClassOf NCIT_C47622 @default.
- NCIT_C47622 subClassOf NCIT_C784 @default.