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- NCIT_C47624 IAO_0000115 "The hydrochloride salt form of molindone, a dihydroindolone compound with antipsychotic and anti-schizophrenic properties not structurally related to other major tranquilizers. Molindone hydrochloride exerts its effect by blocking dopamine receptors, probably D2 and D3, in the reticular activating and limbic systems, thereby decreasing dopamine excess in the brain. This leads to a reduction of spontaneous locomotion and aggressiveness, suppression of conditioned response, antagonism of stereotyped behaviour and hyperactivity induced by amphetamines." @default.
- NCIT_C47624 NCIT_A6 NCIT_C61850 @default.
- NCIT_C47624 NCIT_NHC0 "C47624" @default.
- NCIT_C47624 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47624 NCIT_P108 "Molindone Hydrochloride" @default.
- NCIT_C47624 NCIT_P207 "C0282249" @default.
- NCIT_C47624 NCIT_P210 "15622-65-8" @default.
- NCIT_C47624 NCIT_P319 "1DWS68PNE6" @default.
- NCIT_C47624 NCIT_P322 "FDA" @default.
- NCIT_C47624 NCIT_P350 "C16H24N2O2.HCl" @default.
- NCIT_C47624 NCIT_P366 "Molindone_Hydrochloride" @default.
- NCIT_C47624 normalizedInformationContent "100" @default.
- NCIT_C47624 referenceCount "1" @default.
- NCIT_C47624 hasExactSynonym "4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, Monohydrochloride" @default.
- NCIT_C47624 hasExactSynonym "Lidone" @default.
- NCIT_C47624 hasExactSynonym "MOLINDONE HYDROCHLORIDE" @default.
- NCIT_C47624 hasExactSynonym "Moban" @default.
- NCIT_C47624 hasExactSynonym "Molindone Hydrochloride" @default.
- NCIT_C47624 inSubset NCIT_C63923 @default.
- NCIT_C47624 type Class @default.
- NCIT_C47624 isDefinedBy ncit.owl @default.
- NCIT_C47624 label "Molindone Hydrochloride" @default.
- NCIT_C47624 subClassOf NCIT_C1908 @default.
- NCIT_C47624 subClassOf NCIT_C1909 @default.
- NCIT_C47624 subClassOf NCIT_C29710 @default.
- NCIT_C47624 subClassOf NCIT_C47624 @default.
- NCIT_C47624 subClassOf NCIT_C78272 @default.