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- NCIT_C47636 IAO_0000115 "A recombinant version of the cardiac neurohormone, human B-type natriuretic peptide (hBNP) produced by the ventricular myocardium. Nesiritide binds to natriuretic peptide receptors on vascular smooth muscle and endothelial cells, through which it triggers guanylate cyclase dependent signal transduction resulting in increase of intracellular concentrations of cGMP. This leads to smooth muscle cell relaxation causing arterial and venous dilatation." @default.
- NCIT_C47636 NCIT_A5 NCIT_C95607 @default.
- NCIT_C47636 NCIT_NHC0 "C47636" @default.
- NCIT_C47636 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47636 NCIT_P108 "Nesiritide" @default.
- NCIT_C47636 NCIT_P207 "C0054015" @default.
- NCIT_C47636 NCIT_P210 "124584-08-3" @default.
- NCIT_C47636 NCIT_P319 "P7WI8UL647" @default.
- NCIT_C47636 NCIT_P322 "FDA" @default.
- NCIT_C47636 NCIT_P329 "434520" @default.
- NCIT_C47636 NCIT_P330 "434520" @default.
- NCIT_C47636 NCIT_P350 "C143H244N50O42S4" @default.
- NCIT_C47636 NCIT_P366 "Nesiritide" @default.
- NCIT_C47636 NCIT_P399 "434520" @default.
- NCIT_C47636 normalizedInformationContent "100" @default.
- NCIT_C47636 referenceCount "1" @default.
- NCIT_C47636 hasExactSynonym "1,2-Dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecaazacyclotripentacontane, Cyclic Peptide Derivative" @default.
- NCIT_C47636 hasExactSynonym "Human Brain Natriuretic Factor-32" @default.
- NCIT_C47636 hasExactSynonym "L-Histidine, L-seryl-L-prolyl-L-lysyl-L-methionyl-L-valyl-L-glutaminylglycyl-L-serylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-arginyl-L-lysyl-L-methionyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-L-seryl-L-seryl-L-seryl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-arginyl-, Cyclic (10-26)-disulfide" @default.
- NCIT_C47636 hasExactSynonym "NESIRITIDE" @default.
- NCIT_C47636 hasExactSynonym "Natriuretic Peptide Type-B" @default.
- NCIT_C47636 hasExactSynonym "Natriuretic factor-32" @default.
- NCIT_C47636 hasExactSynonym "Nesiritide" @default.
- NCIT_C47636 inSubset NCIT_C176424 @default.
- NCIT_C47636 inSubset NCIT_C63923 @default.
- NCIT_C47636 type Class @default.
- NCIT_C47636 isDefinedBy ncit.owl @default.
- NCIT_C47636 label "Nesiritide" @default.
- NCIT_C47636 subClassOf NCIT_C1908 @default.
- NCIT_C47636 subClassOf NCIT_C1909 @default.
- NCIT_C47636 subClassOf NCIT_C29707 @default.
- NCIT_C47636 subClassOf NCIT_C47636 @default.
- NCIT_C47636 subClassOf NCIT_C78274 @default.