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- NCIT_C47644 IAO_0000115 "The nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fully elucidated, oxiconazole, like other azole antifungals, most likely inhibits the cytochrome P450-dependent demethylation of lanosterol. This prevents the synthesis of ergosterol which is a crucial component of fungal cell membrane. By disrupting fungal cell membrane synthesis and integrity, oxiconazole alters fungal cell membrane permeability, promotes loss of essential intracellular components and eventually inhibits fungal cell growth." @default.
- NCIT_C47644 NCIT_A6 NCIT_C61869 @default.
- NCIT_C47644 NCIT_NHC0 "C47644" @default.
- NCIT_C47644 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47644 NCIT_P108 "Oxiconazole Nitrate" @default.
- NCIT_C47644 NCIT_P207 "C0142160" @default.
- NCIT_C47644 NCIT_P210 "64211-46-7" @default.
- NCIT_C47644 NCIT_P319 "RQ8UL4C17S" @default.
- NCIT_C47644 NCIT_P322 "FDA" @default.
- NCIT_C47644 NCIT_P350 "C18H13Cl4N3O.HNO3" @default.
- NCIT_C47644 NCIT_P366 "Oxiconazole_Nitrate" @default.
- NCIT_C47644 normalizedInformationContent "100" @default.
- NCIT_C47644 referenceCount "1" @default.
- NCIT_C47644 hasExactSynonym "(Z)-1-(2-(2,4-Dichlorophenyl)-2-(((2,4-dichlorophenyl)oxy)imino)ethyl)-1H-imidazole Mononitrate" @default.
- NCIT_C47644 hasExactSynonym "Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-, O-((2,4-dichlorophenyl)methyl)oxime,(Z)-, Mononitrate" @default.
- NCIT_C47644 hasExactSynonym "OXICONAZOLE NITRATE" @default.
- NCIT_C47644 hasExactSynonym "Oxiconazole Nitrate" @default.
- NCIT_C47644 hasExactSynonym "Oxistat" @default.
- NCIT_C47644 inSubset NCIT_C63923 @default.
- NCIT_C47644 type Class @default.
- NCIT_C47644 isDefinedBy ncit.owl @default.
- NCIT_C47644 label "Oxiconazole Nitrate" @default.
- NCIT_C47644 subClassOf NCIT_C1908 @default.
- NCIT_C47644 subClassOf NCIT_C1909 @default.
- NCIT_C47644 subClassOf NCIT_C254 @default.
- NCIT_C47644 subClassOf NCIT_C47644 @default.
- NCIT_C47644 subClassOf NCIT_C514 @default.