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- NCIT_C47667 IAO_0000115 "A phenylalkylamine sympathomimetic amine with appetite depressant property. Phendimetrazine tartrate is a prodrug that is hydrolyzed to the active metabolite phenmetrazine, which competes with norepinephrine and dopamine for their presynaptic transporters, thereby blocks the reuptake of these monoamines at the neuronal junctions. As a result, this prolongs activities of dopamine and norepinephrine and leads to central nervous system (CNS) stimulation and metabolic effects, including appetite-suppression, decreased gastric acid secretion and increased blood pressure." @default.
- NCIT_C47667 NCIT_A6 NCIT_C61887 @default.
- NCIT_C47667 NCIT_NHC0 "C47667" @default.
- NCIT_C47667 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47667 NCIT_P108 "Phendimetrazine Tartrate" @default.
- NCIT_C47667 NCIT_P175 "91526" @default.
- NCIT_C47667 NCIT_P207 "C0718266" @default.
- NCIT_C47667 NCIT_P210 "21102-82-9" @default.
- NCIT_C47667 NCIT_P210 "50-58-8" @default.
- NCIT_C47667 NCIT_P319 "6985IP0T80" @default.
- NCIT_C47667 NCIT_P322 "FDA" @default.
- NCIT_C47667 NCIT_P350 "C12H17NO.C4H6O6" @default.
- NCIT_C47667 NCIT_P366 "Phendimetrazine_Tartrate" @default.
- NCIT_C47667 normalizedInformationContent "100" @default.
- NCIT_C47667 referenceCount "1" @default.
- NCIT_C47667 hasExactSynonym "(2S,3S)-3,4-Dimethyl-2-phenylmorpholine L-(+)-tartrate(1:1)" @default.
- NCIT_C47667 hasExactSynonym "Adipost" @default.
- NCIT_C47667 hasExactSynonym "Bontril" @default.
- NCIT_C47667 hasExactSynonym "Metra" @default.
- NCIT_C47667 hasExactSynonym "Morpholine, 3,4-dimethyl-2-phenyl-,(2S,3S)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1)" @default.
- NCIT_C47667 hasExactSynonym "PHENDIMETRAZINE TARTRATE" @default.
- NCIT_C47667 hasExactSynonym "Phenazine" @default.
- NCIT_C47667 hasExactSynonym "Phendimetrazine Tartrate" @default.
- NCIT_C47667 hasExactSynonym "Plegine" @default.
- NCIT_C47667 hasExactSynonym "Sprx-105" @default.
- NCIT_C47667 hasExactSynonym "Sprx-3" @default.
- NCIT_C47667 hasExactSynonym "Statobex" @default.
- NCIT_C47667 hasExactSynonym "Statobex-G" @default.
- NCIT_C47667 hasExactSynonym "X-Trozine" @default.
- NCIT_C47667 inSubset NCIT_C63923 @default.
- NCIT_C47667 type Class @default.
- NCIT_C47667 isDefinedBy ncit.owl @default.
- NCIT_C47667 label "Phendimetrazine Tartrate" @default.
- NCIT_C47667 subClassOf NCIT_C1908 @default.
- NCIT_C47667 subClassOf NCIT_C1909 @default.
- NCIT_C47667 subClassOf NCIT_C29728 @default.
- NCIT_C47667 subClassOf NCIT_C47667 @default.
- NCIT_C47667 subClassOf NCIT_C47795 @default.
- NCIT_C47667 subClassOf NCIT_C78272 @default.