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- NCIT_C47669 IAO_0000115 "An ethanolamine derivative with antihistaminic property. Phenyltoloxamine blocks H1 histamine receptors, thereby inhibiting phospholipase A2 and production of endothelium-derived relaxing factor, nitric oxide. Subsequent lack of activation of guanylyl cyclase through nitric oxide results in decreased cyclic GMP levels, thereby inhibiting smooth muscle constriction of various tissues, decreasing capillary permeability and decreasing other histamine-activated allergic reactions." @default.
- NCIT_C47669 NCIT_A5 NCIT_C82275 @default.
- NCIT_C47669 NCIT_A5 NCIT_C97702 @default.
- NCIT_C47669 NCIT_NHC0 "C47669" @default.
- NCIT_C47669 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47669 NCIT_P108 "Phenyltoloxamine" @default.
- NCIT_C47669 NCIT_P207 "C0070709" @default.
- NCIT_C47669 NCIT_P210 "92-12-6" @default.
- NCIT_C47669 NCIT_P319 "K65LB6598J" @default.
- NCIT_C47669 NCIT_P322 "FDA" @default.
- NCIT_C47669 NCIT_P350 "C17H21NO" @default.
- NCIT_C47669 NCIT_P366 "Phenyltoloxamine" @default.
- NCIT_C47669 normalizedInformationContent "100" @default.
- NCIT_C47669 referenceCount "1" @default.
- NCIT_C47669 hasExactSynonym "Antin" @default.
- NCIT_C47669 hasExactSynonym "Bristamin" @default.
- NCIT_C47669 hasExactSynonym "Histionex" @default.
- NCIT_C47669 hasExactSynonym "N,N-Dimethyl-2-(2-(phenylmethyl)phenoxy)ethanamine" @default.
- NCIT_C47669 hasExactSynonym "N,N-Dimethyl-2-(alpha-phenyl-o-tolyloxy)ethylamine" @default.
- NCIT_C47669 hasExactSynonym "PHENYLTOLOXAMINE" @default.
- NCIT_C47669 hasExactSynonym "Phenyltoloxamine" @default.
- NCIT_C47669 inSubset NCIT_C63923 @default.
- NCIT_C47669 type Class @default.
- NCIT_C47669 isDefinedBy ncit.owl @default.
- NCIT_C47669 label "Phenyltoloxamine" @default.
- NCIT_C47669 subClassOf NCIT_C1908 @default.
- NCIT_C47669 subClassOf NCIT_C1909 @default.
- NCIT_C47669 subClassOf NCIT_C29578 @default.
- NCIT_C47669 subClassOf NCIT_C308 @default.
- NCIT_C47669 subClassOf NCIT_C47669 @default.