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- NCIT_C47682 IAO_0000115 "The hydrochloride salt form of pramoxine, a morpholine derivative with local anesthetic property. Pramocaine hydrochloride decreases the permeability of the neuronal membrane to sodium ions by reversibly binding to and inhibiting voltage-gated sodium channels. This results in stabilization of the membrane and, thereby inhibiting the ionic fluxes required for membrane depolarization, hence resulting in the failure to initiate a propagated action potential and subsequent conduction blockade." @default.
- NCIT_C47682 NCIT_A6 NCIT_C61903 @default.
- NCIT_C47682 NCIT_NHC0 "C47682" @default.
- NCIT_C47682 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47682 NCIT_P108 "Pramocaine Hydrochloride" @default.
- NCIT_C47682 NCIT_P175 "25573" @default.
- NCIT_C47682 NCIT_P207 "C0147008" @default.
- NCIT_C47682 NCIT_P210 "637-58-1" @default.
- NCIT_C47682 NCIT_P319 "88AYB867L5" @default.
- NCIT_C47682 NCIT_P322 "FDA" @default.
- NCIT_C47682 NCIT_P350 "C17H27NO3.HCl" @default.
- NCIT_C47682 NCIT_P366 "Pramoxine_Hydrochloride" @default.
- NCIT_C47682 normalizedInformationContent "100" @default.
- NCIT_C47682 referenceCount "1" @default.
- NCIT_C47682 hasExactSynonym "4-(3-(p-Butoxyphenoxy)propyl)morpholine Hydrochloride" @default.
- NCIT_C47682 hasExactSynonym "Fleet" @default.
- NCIT_C47682 hasExactSynonym "PRAMOXINE HYDROCHLORIDE" @default.
- NCIT_C47682 hasExactSynonym "Pramocaine Hydrochloride" @default.
- NCIT_C47682 hasExactSynonym "Pramoxine Hydrochloride" @default.
- NCIT_C47682 hasExactSynonym "Tronolane" @default.
- NCIT_C47682 hasExactSynonym "Tronothane" @default.
- NCIT_C47682 inSubset NCIT_C63923 @default.
- NCIT_C47682 type Class @default.
- NCIT_C47682 isDefinedBy ncit.owl @default.
- NCIT_C47682 label "Pramocaine Hydrochloride" @default.
- NCIT_C47682 subClassOf NCIT_C1908 @default.
- NCIT_C47682 subClassOf NCIT_C1909 @default.
- NCIT_C47682 subClassOf NCIT_C245 @default.
- NCIT_C47682 subClassOf NCIT_C47682 @default.
- NCIT_C47682 subClassOf NCIT_C78272 @default.