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- NCIT_C47706 IAO_0000115 "The hydrochloride salt form of ritodrine, a phenethylamine derivative with tocolytic activity. Ritodrine hydrochloride binds to and activates beta-2 adrenergic receptors of myocytes in the uterine myometrium, which results in decreased intensity and frequency of uterine contraction. Specifically, ritodrine hydrochloride probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhancing the efflux of calcium from vascular smooth muscle cells. A lack of intracellular calcium prevents uterine myometrial contraction. In addition, this agent may directly inactivate myosin light chain kinase, a critical enzyme necessary for the initiation of muscle contractions." @default.
- NCIT_C47706 NCIT_A6 NCIT_C61929 @default.
- NCIT_C47706 NCIT_NHC0 "C47706" @default.
- NCIT_C47706 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47706 NCIT_P108 "Ritodrine Hydrochloride" @default.
- NCIT_C47706 NCIT_P175 "291565" @default.
- NCIT_C47706 NCIT_P207 "C0356649" @default.
- NCIT_C47706 NCIT_P210 "23239-51-2" @default.
- NCIT_C47706 NCIT_P319 "ESJ56Q60GC" @default.
- NCIT_C47706 NCIT_P322 "FDA" @default.
- NCIT_C47706 NCIT_P350 "C17H21NO3.HCl" @default.
- NCIT_C47706 NCIT_P366 "Ritodrine_Hydrochloride" @default.
- NCIT_C47706 normalizedInformationContent "100" @default.
- NCIT_C47706 referenceCount "1" @default.
- NCIT_C47706 hasExactSynonym "Erythro-p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl Alcohol Hydrochloride" @default.
- NCIT_C47706 hasExactSynonym "Pre-Par" @default.
- NCIT_C47706 hasExactSynonym "RITODRINE HYDROCHLORIDE" @default.
- NCIT_C47706 hasExactSynonym "Ritodrine Hydrochloride" @default.
- NCIT_C47706 hasExactSynonym "Yutopar" @default.
- NCIT_C47706 inSubset NCIT_C63923 @default.
- NCIT_C47706 type Class @default.
- NCIT_C47706 isDefinedBy ncit.owl @default.
- NCIT_C47706 label "Ritodrine Hydrochloride" @default.
- NCIT_C47706 subClassOf NCIT_C1908 @default.
- NCIT_C47706 subClassOf NCIT_C1909 @default.
- NCIT_C47706 subClassOf NCIT_C29747 @default.
- NCIT_C47706 subClassOf NCIT_C47706 @default.
- NCIT_C47706 subClassOf NCIT_C48149 @default.
- NCIT_C47706 subClassOf NCIT_C78272 @default.
- NCIT_C47706 subClassOf NCIT_C87053 @default.