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- NCIT_C47746 IAO_0000115 "A benzimidazole derivative and a non-peptide angiotensin II receptor antagonist with antihypertensive property. Telmisartan selectively antagonizes angiotensin II binding to the AT1 subtype receptor, located in vascular smooth muscle and adrenal gland. The antagonism results in vasodilation and inhibits the angiotensin II-mediated aldosterone production, which in turn leading to a decrease in sodium and water as well as an increase in potassium excretion leading to a subsequent reduction in blood pressure." @default.
- NCIT_C47746 NCIT_A7 NCIT_C179874 @default.
- NCIT_C47746 NCIT_NHC0 "C47746" @default.
- NCIT_C47746 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47746 NCIT_P107 "Telmisartan" @default.
- NCIT_C47746 NCIT_P108 "Telmisartan" @default.
- NCIT_C47746 NCIT_P207 "C0248719" @default.
- NCIT_C47746 NCIT_P210 "144701-48-4" @default.
- NCIT_C47746 NCIT_P319 "U5SYW473RQ" @default.
- NCIT_C47746 NCIT_P322 "CTRP" @default.
- NCIT_C47746 NCIT_P322 "FDA" @default.
- NCIT_C47746 NCIT_P350 "C33H30N4O2" @default.
- NCIT_C47746 NCIT_P366 "Telmisartan" @default.
- NCIT_C47746 NCIT_P368 "CHEBI:9434" @default.
- NCIT_C47746 NCIT_P399 "810447" @default.
- NCIT_C47746 normalizedInformationContent "100" @default.
- NCIT_C47746 referenceCount "1" @default.
- NCIT_C47746 hasExactSynonym "(1,1'-Biphenyl)-2-carboxylic Acid, 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-" @default.
- NCIT_C47746 hasExactSynonym "4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic Acid" @default.
- NCIT_C47746 hasExactSynonym "BIBR 277" @default.
- NCIT_C47746 hasExactSynonym "Micardis" @default.
- NCIT_C47746 hasExactSynonym "TELMISARTAN" @default.
- NCIT_C47746 hasExactSynonym "Telmisartan" @default.
- NCIT_C47746 inSubset NCIT_C116977 @default.
- NCIT_C47746 inSubset NCIT_C116978 @default.
- NCIT_C47746 inSubset NCIT_C173381 @default.
- NCIT_C47746 inSubset NCIT_C173383 @default.
- NCIT_C47746 inSubset NCIT_C176424 @default.
- NCIT_C47746 inSubset NCIT_C63923 @default.
- NCIT_C47746 type Class @default.
- NCIT_C47746 isDefinedBy ncit.owl @default.
- NCIT_C47746 label "Telmisartan" @default.
- NCIT_C47746 subClassOf NCIT_C1908 @default.
- NCIT_C47746 subClassOf NCIT_C1909 @default.
- NCIT_C47746 subClassOf NCIT_C270 @default.
- NCIT_C47746 subClassOf NCIT_C47746 @default.
- NCIT_C47746 subClassOf NCIT_C66930 @default.
- NCIT_C47746 subClassOf NCIT_C78274 @default.