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- NCIT_C47766 IAO_0000115 "A synthetic lipophilic isopropyl ester prodrug of the active compound travoprost free acid, a prostaglandin F2alpha analog with anti-glaucoma property. Upon administration, travoprost is hydrolysed to a free acid by corneal esterases, and then selectively stimulating the prostaglandin F (FP prostanoid) receptor, thereby increasing the uveoscleral outflow which leads to a reduction in intra-ocular pressure." @default.
- NCIT_C47766 NCIT_NHC0 "C47766" @default.
- NCIT_C47766 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47766 NCIT_P108 "Travoprost" @default.
- NCIT_C47766 NCIT_P207 "C0937916" @default.
- NCIT_C47766 NCIT_P210 "157283-68-6" @default.
- NCIT_C47766 NCIT_P302 "Glaucoma" @default.
- NCIT_C47766 NCIT_P319 "WJ68R08KX9" @default.
- NCIT_C47766 NCIT_P322 "FDA" @default.
- NCIT_C47766 NCIT_P350 "C26H35F3O6" @default.
- NCIT_C47766 NCIT_P366 "Travoprost" @default.
- NCIT_C47766 NCIT_P368 "CHEBI:746859" @default.
- NCIT_C47766 normalizedInformationContent "100" @default.
- NCIT_C47766 referenceCount "1" @default.
- NCIT_C47766 hasExactSynonym "5-Heptenoic Acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3R)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-, 1-methylethyl Ester,(5Z)-" @default.
- NCIT_C47766 hasExactSynonym "AL-6221" @default.
- NCIT_C47766 hasExactSynonym "TRAVOPROST" @default.
- NCIT_C47766 hasExactSynonym "Travatan Z" @default.
- NCIT_C47766 hasExactSynonym "Travoprost" @default.
- NCIT_C47766 inSubset NCIT_C63923 @default.
- NCIT_C47766 type Class @default.
- NCIT_C47766 isDefinedBy ncit.owl @default.
- NCIT_C47766 label "Travoprost" @default.
- NCIT_C47766 subClassOf NCIT_C1908 @default.
- NCIT_C47766 subClassOf NCIT_C1909 @default.
- NCIT_C47766 subClassOf NCIT_C29705 @default.
- NCIT_C47766 subClassOf NCIT_C47766 @default.
- NCIT_C47766 subClassOf NCIT_C78283 @default.
- NCIT_C47766 subClassOf NCIT_C78568 @default.