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- NCIT_C47767 IAO_0000115 "The hydrochloride salt form of trazodone, a synthetic triazolopyridine derivative with antidepressant and sedative properties. Based on studies from animal models, trazodone selectively inhibits the re-uptake of serotonin by synaptosomes in the brain, thereby increasing serotonin levels in the synaptic cleft and potentiating serotonin activity. Trazodone is not a monoamine oxidase inhibitor and, unlike amphetamine-type drugs, does not stimulate the central nervous system. The sedative effect of trazodone is likely via alpha-adrenergic and mild histamine H1 blocking actions." @default.
- NCIT_C47767 NCIT_A6 NCIT_C29510 @default.
- NCIT_C47767 NCIT_NHC0 "C47767" @default.
- NCIT_C47767 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47767 NCIT_P108 "Trazodone Hydrochloride" @default.
- NCIT_C47767 NCIT_P175 "292811" @default.
- NCIT_C47767 NCIT_P207 "C0701914" @default.
- NCIT_C47767 NCIT_P210 "25332-39-2" @default.
- NCIT_C47767 NCIT_P319 "6E8ZO8LRNM" @default.
- NCIT_C47767 NCIT_P322 "FDA" @default.
- NCIT_C47767 NCIT_P350 "C19H22ClN5O.HCl" @default.
- NCIT_C47767 NCIT_P366 "Trazodone_Hydrochloride" @default.
- NCIT_C47767 NCIT_P368 "CHEBI:9655" @default.
- NCIT_C47767 normalizedInformationContent "100" @default.
- NCIT_C47767 referenceCount "1" @default.
- NCIT_C47767 hasExactSynonym "1,2,4-Triazolo(4,3-a)pyridin-3(2H)-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-, Monohydrochloride" @default.
- NCIT_C47767 hasExactSynonym "2-(3-(4-(3-Chlorophenyl)piperazin-1-y)propyl)-1,2,4-triazolo(4,3-a)pyridine-3(2H)-one Hydrochloride" @default.
- NCIT_C47767 hasExactSynonym "Desyrel" @default.
- NCIT_C47767 hasExactSynonym "TRAZODONE HYDROCHLORIDE" @default.
- NCIT_C47767 hasExactSynonym "Trazodone Hydrochloride" @default.
- NCIT_C47767 hasExactSynonym "Trialodine" @default.
- NCIT_C47767 inSubset NCIT_C63923 @default.
- NCIT_C47767 type Class @default.
- NCIT_C47767 isDefinedBy ncit.owl @default.
- NCIT_C47767 label "Trazodone Hydrochloride" @default.
- NCIT_C47767 subClassOf NCIT_C1908 @default.
- NCIT_C47767 subClassOf NCIT_C1909 @default.
- NCIT_C47767 subClassOf NCIT_C265 @default.
- NCIT_C47767 subClassOf NCIT_C47767 @default.
- NCIT_C47767 subClassOf NCIT_C78272 @default.