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- NCIT_C47957 IAO_0000115 "The sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction." @default.
- NCIT_C47957 NCIT_A6 NCIT_C215 @default.
- NCIT_C47957 NCIT_NHC0 "C47957" @default.
- NCIT_C47957 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47957 NCIT_P107 "Albuterol Sulfate" @default.
- NCIT_C47957 NCIT_P108 "Albuterol Sulfate" @default.
- NCIT_C47957 NCIT_P175 "289928" @default.
- NCIT_C47957 NCIT_P207 "C0543495" @default.
- NCIT_C47957 NCIT_P210 "51022-70-9" @default.
- NCIT_C47957 NCIT_P319 "021SEF3731" @default.
- NCIT_C47957 NCIT_P322 "CTRP" @default.
- NCIT_C47957 NCIT_P322 "FDA" @default.
- NCIT_C47957 NCIT_P329 "41339" @default.
- NCIT_C47957 NCIT_P330 "41339" @default.
- NCIT_C47957 NCIT_P350 "2C13H21NO3.H2O4S" @default.
- NCIT_C47957 NCIT_P366 "Albuterol_Sulfate" @default.
- NCIT_C47957 NCIT_P368 "CHEBI:2550" @default.
- NCIT_C47957 NCIT_P399 "41339" @default.
- NCIT_C47957 normalizedInformationContent "100" @default.
- NCIT_C47957 referenceCount "1" @default.
- NCIT_C47957 hasExactSynonym "ALBUTEROL SULFATE" @default.
- NCIT_C47957 hasExactSynonym "Albuterol Sulfate" @default.
- NCIT_C47957 hasExactSynonym "Proventil" @default.
- NCIT_C47957 hasExactSynonym "Salbutamol Sulphate" @default.
- NCIT_C47957 hasExactSynonym "Ventolin" @default.
- NCIT_C47957 inSubset NCIT_C116977 @default.
- NCIT_C47957 inSubset NCIT_C116978 @default.
- NCIT_C47957 inSubset NCIT_C176424 @default.
- NCIT_C47957 inSubset NCIT_C63923 @default.
- NCIT_C47957 type Class @default.
- NCIT_C47957 isDefinedBy ncit.owl @default.
- NCIT_C47957 label "Albuterol Sulfate" @default.
- NCIT_C47957 subClassOf NCIT_C1908 @default.
- NCIT_C47957 subClassOf NCIT_C1909 @default.
- NCIT_C47957 subClassOf NCIT_C29712 @default.
- NCIT_C47957 subClassOf NCIT_C29747 @default.
- NCIT_C47957 subClassOf NCIT_C319 @default.
- NCIT_C47957 subClassOf NCIT_C47957 @default.
- NCIT_C47957 subClassOf NCIT_C48149 @default.
- NCIT_C47957 subClassOf NCIT_C78272 @default.
- NCIT_C47957 subClassOf NCIT_C78273 @default.
- NCIT_C47957 subClassOf NCIT_C87053 @default.