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- NCIT_C47961 IAO_0000115 "The sodium salt form of azathioprine, a pro-drug of purine analogue with immunosuppressive activity. Azathioprine is converted in vivo to its active metabolite 6-mercaptopurine (6-MP), which substitutes for the normal nucleoside and mistakenly gets incorporated into DNA sequences. This leads to inhibition of DNA, RNA, and protein synthesis. As a result, cell proliferation may be inhibited, particularly in lymphocytes and leukocytes." @default.
- NCIT_C47961 NCIT_A6 NCIT_C290 @default.
- NCIT_C47961 NCIT_NHC0 "C47961" @default.
- NCIT_C47961 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47961 NCIT_P108 "Azathioprine Sodium" @default.
- NCIT_C47961 NCIT_P207 "C0887732" @default.
- NCIT_C47961 NCIT_P210 "55774-33-9" @default.
- NCIT_C47961 NCIT_P319 "AM94R510MS" @default.
- NCIT_C47961 NCIT_P322 "FDA" @default.
- NCIT_C47961 NCIT_P325 "A drug used to keep a patient from rejecting a transplanted kidney. It is also used in the treatment of rheumatoid arthritis that does not get better with other types of treatment. Azathioprine sodium blocks the growth of white blood cells and the synthesis of DNA, RNA, and protein. It is a type of immunosuppressant." @default.
- NCIT_C47961 NCIT_P329 "39157" @default.
- NCIT_C47961 NCIT_P330 "39157" @default.
- NCIT_C47961 NCIT_P350 "C9H6N7O2S.Na" @default.
- NCIT_C47961 NCIT_P366 "Azathioprine_Sodium" @default.
- NCIT_C47961 NCIT_P399 "39157" @default.
- NCIT_C47961 normalizedInformationContent "100" @default.
- NCIT_C47961 referenceCount "1" @default.
- NCIT_C47961 hasExactSynonym "AZATHIOPRINE SODIUM" @default.
- NCIT_C47961 hasExactSynonym "Azathioprine Sodium" @default.
- NCIT_C47961 hasExactSynonym "Imuran" @default.
- NCIT_C47961 hasExactSynonym "Imurel" @default.
- NCIT_C47961 hasExactSynonym "azathioprine sodium" @default.
- NCIT_C47961 inSubset NCIT_C176424 @default.
- NCIT_C47961 inSubset NCIT_C63923 @default.
- NCIT_C47961 type Class @default.
- NCIT_C47961 isDefinedBy ncit.owl @default.
- NCIT_C47961 label "Azathioprine Sodium" @default.
- NCIT_C47961 subClassOf NCIT_C1556 @default.
- NCIT_C47961 subClassOf NCIT_C186664 @default.
- NCIT_C47961 subClassOf NCIT_C1908 @default.
- NCIT_C47961 subClassOf NCIT_C1909 @default.
- NCIT_C47961 subClassOf NCIT_C272 @default.
- NCIT_C47961 subClassOf NCIT_C274 @default.
- NCIT_C47961 subClassOf NCIT_C308 @default.
- NCIT_C47961 subClassOf NCIT_C47961 @default.
- NCIT_C47961 subClassOf NCIT_C574 @default.