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- NCIT_C47967 IAO_0000115 "The sodium salt form of cefamandole, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis." @default.
- NCIT_C47967 NCIT_A6 NCIT_C353 @default.
- NCIT_C47967 NCIT_NHC0 "C47967" @default.
- NCIT_C47967 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47967 NCIT_P108 "Cefamandole Sodium" @default.
- NCIT_C47967 NCIT_P207 "C1707322" @default.
- NCIT_C47967 NCIT_P210 "30034-03-8" @default.
- NCIT_C47967 NCIT_P319 "IY6234ODVR" @default.
- NCIT_C47967 NCIT_P322 "FDA" @default.
- NCIT_C47967 NCIT_P350 "C18H17N6O5S2.Na" @default.
- NCIT_C47967 NCIT_P366 "Cefamandole_Sodium" @default.
- NCIT_C47967 normalizedInformationContent "100" @default.
- NCIT_C47967 referenceCount "1" @default.
- NCIT_C47967 hasExactSynonym "CEFAMANDOLE SODIUM" @default.
- NCIT_C47967 hasExactSynonym "Cefamandole Sodium" @default.
- NCIT_C47967 hasExactSynonym "D-7-Mandelamido-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, Monosodium Salt" @default.
- NCIT_C47967 inSubset NCIT_C63923 @default.
- NCIT_C47967 type Class @default.
- NCIT_C47967 isDefinedBy ncit.owl @default.
- NCIT_C47967 label "Cefamandole Sodium" @default.
- NCIT_C47967 subClassOf NCIT_C1908 @default.
- NCIT_C47967 subClassOf NCIT_C1909 @default.
- NCIT_C47967 subClassOf NCIT_C254 @default.
- NCIT_C47967 subClassOf NCIT_C258 @default.
- NCIT_C47967 subClassOf NCIT_C260 @default.
- NCIT_C47967 subClassOf NCIT_C357 @default.
- NCIT_C47967 subClassOf NCIT_C47967 @default.