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- NCIT_C47968 IAO_0000115 "The sodium salt of cefazolin, a beta-lactam antibiotic and first-generation cephalosporin with bactericidal activity. Cefazolin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, which results in the weakening of the bacterial cell wall and cell lysis." @default.
- NCIT_C47968 NCIT_A6 NCIT_C28913 @default.
- NCIT_C47968 NCIT_NHC0 "C47968" @default.
- NCIT_C47968 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47968 NCIT_P108 "Cefazolin Sodium" @default.
- NCIT_C47968 NCIT_P175 "291561" @default.
- NCIT_C47968 NCIT_P207 "C0700526" @default.
- NCIT_C47968 NCIT_P210 "27164-46-1" @default.
- NCIT_C47968 NCIT_P319 "P380M0454Z" @default.
- NCIT_C47968 NCIT_P322 "FDA" @default.
- NCIT_C47968 NCIT_P329 "640180" @default.
- NCIT_C47968 NCIT_P330 "640180" @default.
- NCIT_C47968 NCIT_P350 "C14H13N8O4S3.Na" @default.
- NCIT_C47968 NCIT_P366 "Cefazolin_Sodium" @default.
- NCIT_C47968 NCIT_P368 "CHEBI:3483" @default.
- NCIT_C47968 NCIT_P399 "640180" @default.
- NCIT_C47968 normalizedInformationContent "100" @default.
- NCIT_C47968 referenceCount "1" @default.
- NCIT_C47968 hasExactSynonym "(6R-trans)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(((1H-tetrazol-1-yl)acetyl)amino)-5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, Sodium Salt" @default.
- NCIT_C47968 hasExactSynonym "Ancef" @default.
- NCIT_C47968 hasExactSynonym "CEFAZOLIN SODIUM" @default.
- NCIT_C47968 hasExactSynonym "Cefazolin Sodium" @default.
- NCIT_C47968 hasExactSynonym "Kefzol" @default.
- NCIT_C47968 hasExactSynonym "SKF 41558" @default.
- NCIT_C47968 inSubset NCIT_C176424 @default.
- NCIT_C47968 inSubset NCIT_C63923 @default.
- NCIT_C47968 type Class @default.
- NCIT_C47968 isDefinedBy ncit.owl @default.
- NCIT_C47968 label "Cefazolin Sodium" @default.
- NCIT_C47968 subClassOf NCIT_C1908 @default.
- NCIT_C47968 subClassOf NCIT_C1909 @default.
- NCIT_C47968 subClassOf NCIT_C254 @default.
- NCIT_C47968 subClassOf NCIT_C258 @default.
- NCIT_C47968 subClassOf NCIT_C260 @default.
- NCIT_C47968 subClassOf NCIT_C357 @default.
- NCIT_C47968 subClassOf NCIT_C47968 @default.