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- NCIT_C47975 IAO_0000115 "The hydrochloride salt form of chlorpromazine, a phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine hydrochloride exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, such as hallucinations and delusions. Chlorpromazine hydrochloride appears to exert its anti-emetic activity by blocking the dopamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting." @default.
- NCIT_C47975 NCIT_A6 NCIT_C367 @default.
- NCIT_C47975 NCIT_NHC0 "C47975" @default.
- NCIT_C47975 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47975 NCIT_P108 "Chlorpromazine Hydrochloride" @default.
- NCIT_C47975 NCIT_P175 "17479" @default.
- NCIT_C47975 NCIT_P207 "C0355077" @default.
- NCIT_C47975 NCIT_P210 "69-09-0" @default.
- NCIT_C47975 NCIT_P319 "9WP59609J6" @default.
- NCIT_C47975 NCIT_P322 "FDA" @default.
- NCIT_C47975 NCIT_P350 "C17H19ClN2S.HCl" @default.
- NCIT_C47975 NCIT_P366 "Chlorpromazine_Hydrochloride" @default.
- NCIT_C47975 NCIT_P368 "CHEBI:3649" @default.
- NCIT_C47975 normalizedInformationContent "100" @default.
- NCIT_C47975 referenceCount "1" @default.
- NCIT_C47975 hasExactSynonym "2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine Monohydrochloride" @default.
- NCIT_C47975 hasExactSynonym "CHLORPROMAZINE HYDROCHLORIDE" @default.
- NCIT_C47975 hasExactSynonym "Chlorpromazine Hydrochloride" @default.
- NCIT_C47975 inSubset NCIT_C63923 @default.
- NCIT_C47975 type Class @default.
- NCIT_C47975 isDefinedBy ncit.owl @default.
- NCIT_C47975 label "Chlorpromazine Hydrochloride" @default.
- NCIT_C47975 subClassOf NCIT_C1908 @default.
- NCIT_C47975 subClassOf NCIT_C1909 @default.
- NCIT_C47975 subClassOf NCIT_C267 @default.
- NCIT_C47975 subClassOf NCIT_C29710 @default.
- NCIT_C47975 subClassOf NCIT_C47975 @default.
- NCIT_C47975 subClassOf NCIT_C740 @default.
- NCIT_C47975 subClassOf NCIT_C78272 @default.