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- NCIT_C48186 IAO_0000115 "This process is initiated by the formation of heterochromatin which ultimately leads to transcriptional inactivation or silencing. Once formed, heterochromatin can be inherited through many cell divisions, including meiosis. Inappropriate gain of heterochromatin structure, such as the inactivation of tumor suppressor genes by DNA hyper-methylation at their promoter regions, can be directly linked to carcinogenesis." @default.
- NCIT_C48186 NCIT_NHC0 "C48186" @default.
- NCIT_C48186 NCIT_P106 "Genetic Function" @default.
- NCIT_C48186 NCIT_P108 "Epigenetic Silencing" @default.
- NCIT_C48186 NCIT_P207 "C1707931" @default.
- NCIT_C48186 NCIT_P366 "Epigenetic_Silencing" @default.
- NCIT_C48186 normalizedInformationContent "74.665259135057511" @default.
- NCIT_C48186 referenceCount "46" @default.
- NCIT_C48186 hasExactSynonym "Epigenetic Silencing" @default.
- NCIT_C48186 type Class @default.
- NCIT_C48186 isDefinedBy ncit.owl @default.
- NCIT_C48186 label "Epigenetic Silencing" @default.
- NCIT_C48186 subClassOf NCIT_C17710 @default.
- NCIT_C48186 subClassOf NCIT_C17828 @default.
- NCIT_C48186 subClassOf NCIT_C21049 @default.
- NCIT_C48186 subClassOf NCIT_C21050 @default.
- NCIT_C48186 subClassOf NCIT_C21051 @default.
- NCIT_C48186 subClassOf NCIT_C28498 @default.
- NCIT_C48186 subClassOf NCIT_C48186 @default.