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- NCIT_C48194 IAO_0000115 "A steroid hormone produced in the skin when exposed to ultraviolet light or obtained from dietary sources. The active form of cholecalciferol, 1,25-dihydroxycholecalciferol (calcitriol) plays an important role in maintaining blood calcium and phosphorus levels and mineralization of bone. The activated form of cholecalciferol binds to vitamin D receptors and modulates gene expression. This leads to an increase in serum calcium concentrations by increasing intestinal absorption of phosphorus and calcium, promoting distal renal tubular reabsorption of calcium and increasing osteoclastic resorption." @default.
- NCIT_C48194 NCIT_A7 NCIT_C17485 @default.
- NCIT_C48194 NCIT_NHC0 "C48194" @default.
- NCIT_C48194 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C48194 NCIT_P106 "Vitamin" @default.
- NCIT_C48194 NCIT_P107 "Cholecalciferol" @default.
- NCIT_C48194 NCIT_P108 "Cholecalciferol" @default.
- NCIT_C48194 NCIT_P175 "375571" @default.
- NCIT_C48194 NCIT_P207 "C0008318" @default.
- NCIT_C48194 NCIT_P210 "67-97-0" @default.
- NCIT_C48194 NCIT_P319 "1C6V77QF41" @default.
- NCIT_C48194 NCIT_P322 "CRCH" @default.
- NCIT_C48194 NCIT_P322 "CTRP" @default.
- NCIT_C48194 NCIT_P322 "FDA" @default.
- NCIT_C48194 NCIT_P325 "A nutrient that the body needs in small amounts to function and stay healthy. Cholecalciferol helps the body use calcium and phosphorus to make strong bones and teeth. It is fat-soluble (can dissolve in fats and oils) and is found in fatty fish, egg yolks, and dairy products. Skin exposed to sunshine can also make cholecalciferol. Not enough cholecalciferol can cause a bone disease called rickets. It is being studied in the prevention and treatment of some types of cancer." @default.
- NCIT_C48194 NCIT_P325 "Vitamin D synthesized from ergosterol in yeast and plants." @default.
- NCIT_C48194 NCIT_P329 "39734" @default.
- NCIT_C48194 NCIT_P330 "39734" @default.
- NCIT_C48194 NCIT_P350 "C27H44O" @default.
- NCIT_C48194 NCIT_P355 "mcg" @default.
- NCIT_C48194 NCIT_P366 "Cholecalciferol" @default.
- NCIT_C48194 NCIT_P368 "CHEBI:28940" @default.
- NCIT_C48194 NCIT_P399 "39734" @default.
- NCIT_C48194 normalizedInformationContent "100" @default.
- NCIT_C48194 referenceCount "1" @default.
- NCIT_C48194 hasExactSynonym "(3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol" @default.
- NCIT_C48194 hasExactSynonym "9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol" @default.
- NCIT_C48194 hasExactSynonym "9,10-Secocholesta-5,7,10(19)-trien-3-ol" @default.
- NCIT_C48194 hasExactSynonym "CHOLECALCIFEROL" @default.
- NCIT_C48194 hasExactSynonym "Calciol" @default.
- NCIT_C48194 hasExactSynonym "Cholecalciferol" @default.
- NCIT_C48194 hasExactSynonym "Delsterol" @default.
- NCIT_C48194 hasExactSynonym "Vitamin D3" @default.
- NCIT_C48194 hasExactSynonym "cholecalciferol" @default.
- NCIT_C48194 inSubset NCIT_C116977 @default.
- NCIT_C48194 inSubset NCIT_C116978 @default.
- NCIT_C48194 inSubset NCIT_C173381 @default.
- NCIT_C48194 inSubset NCIT_C173383 @default.
- NCIT_C48194 inSubset NCIT_C176424 @default.
- NCIT_C48194 inSubset NCIT_C63923 @default.
- NCIT_C48194 type Class @default.
- NCIT_C48194 isDefinedBy ncit.owl @default.
- NCIT_C48194 label "Cholecalciferol" @default.
- NCIT_C48194 subClassOf NCIT_C1550 @default.
- NCIT_C48194 subClassOf NCIT_C1908 @default.
- NCIT_C48194 subClassOf NCIT_C1930 @default.
- NCIT_C48194 subClassOf NCIT_C1949 @default.
- NCIT_C48194 subClassOf NCIT_C48194 @default.
- NCIT_C48194 subClassOf NCIT_C54060 @default.
- NCIT_C48194 subClassOf NCIT_C941 @default.
- NCIT_C48194 subClassOf NCIT_C944 @default.