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- NCIT_C48280 IAO_0000115 "Hyperfunction of the parathyroid glands resulting in the overproduction of parathyroid hormone. It is caused by parathyroid adenoma, parathyroid hyperplasia, parathyroid carcinoma, and multiple endocrine neoplasia. It is associated with hypercalcemia and hypophosphatemia. Signs and symptoms include weakness, fatigue, nausea, vomiting, constipation, depression, bone pain, osteoporosis, cystic bone lesions, and kidney stones." @default.
- NCIT_C48280 NCIT_NHC0 "C48280" @default.
- NCIT_C48280 NCIT_P106 "Disease or Syndrome" @default.
- NCIT_C48280 NCIT_P108 "Primary Hyperparathyroidism" @default.
- NCIT_C48280 NCIT_P207 "C0221002" @default.
- NCIT_C48280 NCIT_P322 "MedDRA" @default.
- NCIT_C48280 NCIT_P322 "NICHD" @default.
- NCIT_C48280 NCIT_P325 "Hyperparathyroidism due to a condition originating within the parathyroid glands, resulting in hypercalcemia due to increased release of calcium and phosphate from bone matrix, increased renal calcium reabsorption, and increased renal production of 1,25-dihydroxyvitamin D, which increases intestinal absorption of calcium. Primary hyperparathyroidism is also associated with hypophosphatemia as a result of phosphaturia. Clinical features include weakness, fatigue, nausea, vomiting, constipation, depression, and, if chronic, bone pain, osteoporosis, cystic bone lesions, and kidney stones." @default.
- NCIT_C48280 NCIT_P366 "Primary_Hyperparathyroidism" @default.
- NCIT_C48280 NCIT_P375 "Primary hyperparathyroidism" @default.
- NCIT_C48280 NCIT_R100 NCIT_C12219 @default.
- NCIT_C48280 NCIT_R100 NCIT_C12418 @default.
- NCIT_C48280 NCIT_R100 NCIT_C12680 @default.
- NCIT_C48280 NCIT_R100 NCIT_C12704 @default.
- NCIT_C48280 NCIT_R100 NCIT_C12765 @default.
- NCIT_C48280 NCIT_R100 NCIT_C13018 @default.
- NCIT_C48280 NCIT_R100 NCIT_C13063 @default.
- NCIT_C48280 NCIT_R100 NCIT_C13319 @default.
- NCIT_C48280 normalizedInformationContent "81.252167948509552" @default.
- NCIT_C48280 referenceCount "17" @default.
- NCIT_C48280 hasExactSynonym "Primary Hyperparathyroidism" @default.
- NCIT_C48280 inSubset NCIT_C118464 @default.
- NCIT_C48280 inSubset NCIT_C118467 @default.
- NCIT_C48280 inSubset NCIT_C189762 @default.
- NCIT_C48280 inSubset NCIT_C90259 @default.
- NCIT_C48280 type Class @default.
- NCIT_C48280 isDefinedBy ncit.owl @default.
- NCIT_C48280 label "Primary Hyperparathyroidism" @default.
- NCIT_C48280 subClassOf NCIT_C26844 @default.
- NCIT_C48280 subClassOf NCIT_C27551 @default.
- NCIT_C48280 subClassOf NCIT_C27568 @default.
- NCIT_C48280 subClassOf NCIT_C27571 @default.
- NCIT_C48280 subClassOf NCIT_C27648 @default.
- NCIT_C48280 subClassOf NCIT_C27660 @default.
- NCIT_C48280 subClassOf NCIT_C27663 @default.
- NCIT_C48280 subClassOf NCIT_C2991 @default.
- NCIT_C48280 subClassOf NCIT_C3009 @default.
- NCIT_C48280 subClassOf NCIT_C48259 @default.
- NCIT_C48280 subClassOf NCIT_C48280 @default.
- NCIT_C48280 subClassOf NCIT_C53529 @default.
- NCIT_C48280 subClassOf NCIT_C53531 @default.
- NCIT_C48280 subClassOf NCIT_C7057 @default.