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- NCIT_C486 IAO_0000115 "A semisynthetic estrogen. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. This agent also inhibits 5-alpha reductase in epididymal tissue, which lowers testosterone levels and may delay progression of prostatic cancer. In addition to its antineoplastic effects, ethinyl estradiol protects against osteoporosis. In animal models, short-term therapy with this agent has been shown to provide long-term protection against breast cancer, mimicking the antitumor effects of pregnancy. (NCI04)" @default.
- NCIT_C486 NCIT_A32 NCIT_C1909 @default.
- NCIT_C486 NCIT_A7 NCIT_C38361 @default.
- NCIT_C486 NCIT_NHC0 "C486" @default.
- NCIT_C486 NCIT_P106 "Organic Chemical" @default.
- NCIT_C486 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C486 NCIT_P107 "Ethinyl Estradiol" @default.
- NCIT_C486 NCIT_P108 "Ethinyl Estradiol" @default.
- NCIT_C486 NCIT_P175 "10973" @default.
- NCIT_C486 NCIT_P207 "C0015011" @default.
- NCIT_C486 NCIT_P210 "57-63-6" @default.
- NCIT_C486 NCIT_P302 "Advanced androgen-dependent prostate cancer, palliative; Breast cancer, palliative; Estrogen replacement; Menopausal symptoms; Postmenopausal osteoporosis" @default.
- NCIT_C486 NCIT_P319 "423D2T571U" @default.
- NCIT_C486 NCIT_P322 "CTRP" @default.
- NCIT_C486 NCIT_P322 "FDA" @default.
- NCIT_C486 NCIT_P322 "GDC" @default.
- NCIT_C486 NCIT_P329 "39238" @default.
- NCIT_C486 NCIT_P330 "39238" @default.
- NCIT_C486 NCIT_P350 "C20H24O2" @default.
- NCIT_C486 NCIT_P366 "Ethinyl_Estradiol" @default.
- NCIT_C486 NCIT_P368 "CHEBI:4903" @default.
- NCIT_C486 NCIT_P375 "Ethinyl Estradiol" @default.
- NCIT_C486 NCIT_P399 "39238" @default.
- NCIT_C486 NCIT_R122 NCIT_C16484 @default.
- NCIT_C486 NCIT_R122 NCIT_C16486 @default.
- NCIT_C486 NCIT_R122 NCIT_C16554 @default.
- NCIT_C486 NCIT_R122 NCIT_C16865 @default.
- NCIT_C486 NCIT_R122 NCIT_C16946 @default.
- NCIT_C486 NCIT_R122 NCIT_C17021 @default.
- NCIT_C486 NCIT_R122 NCIT_C17573 @default.
- NCIT_C486 NCIT_R122 NCIT_C17673 @default.
- NCIT_C486 NCIT_R122 NCIT_C20027 @default.
- NCIT_C486 NCIT_R122 NCIT_C26548 @default.
- NCIT_C486 NCIT_R122 NCIT_C28459 @default.
- NCIT_C486 NCIT_R122 NCIT_C45999 @default.
- NCIT_C486 NCIT_R122 NCIT_C46000 @default.
- NCIT_C486 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C486 referenceCount "3" @default.
- NCIT_C486 hasExactSynonym "(17alpha)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol" @default.
- NCIT_C486 hasExactSynonym "Diogyn E" @default.
- NCIT_C486 hasExactSynonym "Diogyn-E" @default.
- NCIT_C486 hasExactSynonym "ETHINYL ESTRADIOL" @default.
- NCIT_C486 hasExactSynonym "Estinyl" @default.
- NCIT_C486 hasExactSynonym "Ethinoral" @default.
- NCIT_C486 hasExactSynonym "Ethinyl Estradiol" @default.
- NCIT_C486 hasExactSynonym "Ethinylestradiol" @default.
- NCIT_C486 hasExactSynonym "Eticylol" @default.
- NCIT_C486 hasExactSynonym "Feminone" @default.
- NCIT_C486 hasExactSynonym "Inestra" @default.
- NCIT_C486 hasExactSynonym "Lynoral" @default.
- NCIT_C486 hasExactSynonym "Orestralyn" @default.
- NCIT_C486 inSubset NCIT_C116977 @default.
- NCIT_C486 inSubset NCIT_C116978 @default.
- NCIT_C486 inSubset NCIT_C128784 @default.
- NCIT_C486 inSubset NCIT_C157711 @default.
- NCIT_C486 inSubset NCIT_C157712 @default.
- NCIT_C486 inSubset NCIT_C176424 @default.
- NCIT_C486 inSubset NCIT_C177537 @default.
- NCIT_C486 inSubset NCIT_C63923 @default.
- NCIT_C486 type Class @default.
- NCIT_C486 isDefinedBy ncit.owl @default.
- NCIT_C486 label "Ethinyl Estradiol" @default.
- NCIT_C486 subClassOf NCIT_C147908 @default.
- NCIT_C486 subClassOf NCIT_C1636 @default.
- NCIT_C486 subClassOf NCIT_C1908 @default.
- NCIT_C486 subClassOf NCIT_C1909 @default.
- NCIT_C486 subClassOf NCIT_C2181 @default.
- NCIT_C486 subClassOf NCIT_C478 @default.
- NCIT_C486 subClassOf NCIT_C483 @default.
- NCIT_C486 subClassOf NCIT_C486 @default.
- NCIT_C486 subClassOf NCIT_C548 @default.