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- NCIT_C48638 IAO_0000115 "A cancer vaccine consisting of an inactivated recombinant vaccinia virus encoding epitope peptides derived from melanoma-related HLA-A2-restricted tumor-associated antigens (TAAs), including Melan-A(27-35), gp100(280-288) and tyrosinase(1-9), and two co-stimulatory B7 proteins, B7.1 (CD80) and B7.2 (CD86). Upon administration, recombinant vaccinia-multiepitope melanoma peptides-B7.1-B7.2 vaccine may stimulate a cytotoxic T-lymphocyte response against melanoma cells that express TAAs which share epitopes with the epitope peptides expressed by the vaccine viral vector, resulting in tumor cell lysis; vaccine viral vector-expressed co-stimulatory proteins B7.1 and B7.2 may enhance the cytotoxic T-lymphocyte immune response to the TAAs." @default.
- NCIT_C48638 NCIT_NHC0 "C48638" @default.
- NCIT_C48638 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C48638 NCIT_P108 "Recombinant Vaccinia-Multiepitope Melanoma Peptides-B7.1-B7.2 Vaccine" @default.
- NCIT_C48638 NCIT_P207 "C1709860" @default.
- NCIT_C48638 NCIT_P329 "445463" @default.
- NCIT_C48638 NCIT_P330 "445463" @default.
- NCIT_C48638 NCIT_P366 "Recombinant_Vaccinia-Multiepitope_Melanoma_Peptides-B7_1-B7_2_Vaccine" @default.
- NCIT_C48638 NCIT_P399 "445463" @default.
- NCIT_C48638 normalizedInformationContent "100" @default.
- NCIT_C48638 referenceCount "1" @default.
- NCIT_C48638 hasExactSynonym "Recombinant Vaccinia-Multiepitope Melanoma Peptides-B7.1-B7.2 Vaccine" @default.
- NCIT_C48638 inSubset NCIT_C128784 @default.
- NCIT_C48638 inSubset NCIT_C176424 @default.
- NCIT_C48638 type Class @default.
- NCIT_C48638 isDefinedBy ncit.owl @default.
- NCIT_C48638 label "Recombinant Vaccinia-Multiepitope Melanoma Peptides-B7.1-B7.2 Vaccine" @default.
- NCIT_C48638 subClassOf NCIT_C1572 @default.
- NCIT_C48638 subClassOf NCIT_C1908 @default.
- NCIT_C48638 subClassOf NCIT_C1909 @default.
- NCIT_C48638 subClassOf NCIT_C2313 @default.
- NCIT_C48638 subClassOf NCIT_C307 @default.
- NCIT_C48638 subClassOf NCIT_C308 @default.
- NCIT_C48638 subClassOf NCIT_C48638 @default.
- NCIT_C48638 subClassOf NCIT_C923 @default.
- NCIT_C48638 subClassOf NCIT_C96404 @default.