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- NCIT_C48812 IAO_0000115 "A novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase." @default.
- NCIT_C48812 NCIT_A32 NCIT_C1909 @default.
- NCIT_C48812 NCIT_A7 NCIT_C16682 @default.
- NCIT_C48812 NCIT_NHC0 "C48812" @default.
- NCIT_C48812 NCIT_P106 "Organic Chemical" @default.
- NCIT_C48812 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C48812 NCIT_P107 "Belinostat" @default.
- NCIT_C48812 NCIT_P108 "Belinostat" @default.
- NCIT_C48812 NCIT_P175 "726630" @default.
- NCIT_C48812 NCIT_P207 "C1948068" @default.
- NCIT_C48812 NCIT_P210 "414864-00-9" @default.
- NCIT_C48812 NCIT_P302 "relapsed or refractory peripheral T-cell lymphoma (PTCL)" @default.
- NCIT_C48812 NCIT_P319 "F4H96P17NZ" @default.
- NCIT_C48812 NCIT_P322 "CTRP" @default.
- NCIT_C48812 NCIT_P322 "FDA" @default.
- NCIT_C48812 NCIT_P322 "GDC" @default.
- NCIT_C48812 NCIT_P325 "A substance being studied in the treatment of cancer. Belinostat blocks enzymes needed for cell division and may kill cancer cells. It also prevents the growth of blood vessels needed for tumors to grow and may make tumor cells more sensitive to other anticancer drugs. It is a type of histone deacetylase (HDAC) inhibitor, a type of angiogenesis inhibitor, and a type of chemosensitizer." @default.
- NCIT_C48812 NCIT_P329 "454583" @default.
- NCIT_C48812 NCIT_P330 "454583" @default.
- NCIT_C48812 NCIT_P350 "C15H14N2O4S" @default.
- NCIT_C48812 NCIT_P366 "PXD101" @default.
- NCIT_C48812 NCIT_P368 "CHEBI:61076" @default.
- NCIT_C48812 NCIT_P375 "Belinostat" @default.
- NCIT_C48812 NCIT_P399 "454583" @default.
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- NCIT_C48812 NCIT_R125 NCIT_C51037 @default.
- NCIT_C48812 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C48812 referenceCount "2" @default.
- NCIT_C48812 hasExactSynonym "BELINOSTAT" @default.
- NCIT_C48812 hasExactSynonym "Beleodaq" @default.
- NCIT_C48812 hasExactSynonym "Belinostat" @default.
- NCIT_C48812 hasExactSynonym "PXD 101" @default.
- NCIT_C48812 hasExactSynonym "PXD101" @default.
- NCIT_C48812 hasExactSynonym "belinostat" @default.
- NCIT_C48812 inSubset NCIT_C116977 @default.
- NCIT_C48812 inSubset NCIT_C116978 @default.
- NCIT_C48812 inSubset NCIT_C128784 @default.
- NCIT_C48812 inSubset NCIT_C157711 @default.
- NCIT_C48812 inSubset NCIT_C157712 @default.
- NCIT_C48812 inSubset NCIT_C176424 @default.
- NCIT_C48812 inSubset NCIT_C177537 @default.
- NCIT_C48812 inSubset NCIT_C63923 @default.
- NCIT_C48812 type Class @default.
- NCIT_C48812 isDefinedBy ncit.owl @default.
- NCIT_C48812 label "Belinostat" @default.
- NCIT_C48812 subClassOf B02ae5d1fe57323f5391678fba8b84b4c @default.
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- NCIT_C48812 subClassOf NCIT_C1908 @default.
- NCIT_C48812 subClassOf NCIT_C1909 @default.
- NCIT_C48812 subClassOf NCIT_C1946 @default.
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- NCIT_C48812 subClassOf NCIT_C48812 @default.