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- NCIT_C49061 IAO_0000115 "A small molecule and non-prodrug analogue of the lipophilic macrolide antibiotic rapamycin with potential antitumor activity. Ridaforolimus binds to and inhibits the mammalian target of rapamycin (mTOR), which may result in cell cycle arrest and, consequently, the inhibition of tumor cell growth and proliferation. Upregulated in some tumors, mTOR is a serine/threonine kinase involved in regulating cellular proliferation, motility, and survival that is located downstream of the PI3K/Akt signaling pathway." @default.
- NCIT_C49061 NCIT_A32 NCIT_C1909 @default.
- NCIT_C49061 NCIT_A7 NCIT_C38929 @default.
- NCIT_C49061 NCIT_NHC0 "C49061" @default.
- NCIT_C49061 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C49061 NCIT_P107 "Ridaforolimus" @default.
- NCIT_C49061 NCIT_P108 "Ridaforolimus" @default.
- NCIT_C49061 NCIT_P207 "C2713007" @default.
- NCIT_C49061 NCIT_P210 "572924-54-0" @default.
- NCIT_C49061 NCIT_P319 "48Z35KB15K" @default.
- NCIT_C49061 NCIT_P322 "CTRP" @default.
- NCIT_C49061 NCIT_P322 "FDA" @default.
- NCIT_C49061 NCIT_P322 "GDC" @default.
- NCIT_C49061 NCIT_P325 "A substance being studied in the treatment of soft tissue and bone cancers. It is also being studied in the treatment of other solid tumors and hematologic cancer. Ridaforolimus stops cells from dividing and may cause cancer cells to die. It is a type of mTOR inhibitor." @default.
- NCIT_C49061 NCIT_P329 "354223" @default.
- NCIT_C49061 NCIT_P330 "354223" @default.
- NCIT_C49061 NCIT_P350 "C53H84NO14P" @default.
- NCIT_C49061 NCIT_P366 "AP23573" @default.
- NCIT_C49061 NCIT_P375 "Ridaforolimus" @default.
- NCIT_C49061 NCIT_P399 "354223" @default.
- NCIT_C49061 NCIT_R124 NCIT_C17710 @default.
- NCIT_C49061 NCIT_R124 NCIT_C17828 @default.
- NCIT_C49061 NCIT_R124 NCIT_C28498 @default.
- NCIT_C49061 NCIT_R124 NCIT_C40576 @default.
- NCIT_C49061 NCIT_R124 NCIT_C40577 @default.
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- NCIT_C49061 NCIT_R125 NCIT_C20480 @default.
- NCIT_C49061 NCIT_R125 NCIT_C40821 @default.
- NCIT_C49061 NCIT_R146 NCIT_C16554 @default.
- NCIT_C49061 NCIT_R146 NCIT_C16984 @default.
- NCIT_C49061 NCIT_R146 NCIT_C17018 @default.
- NCIT_C49061 NCIT_R146 NCIT_C17021 @default.
- NCIT_C49061 NCIT_R146 NCIT_C17210 @default.
- NCIT_C49061 NCIT_R146 NCIT_C17325 @default.
- NCIT_C49061 NCIT_R146 NCIT_C20027 @default.
- NCIT_C49061 NCIT_R146 NCIT_C26548 @default.
- NCIT_C49061 NCIT_R146 NCIT_C38929 @default.
- NCIT_C49061 normalizedInformationContent "100" @default.
- NCIT_C49061 referenceCount "1" @default.
- NCIT_C49061 hasExactSynonym "AP23573" @default.
- NCIT_C49061 hasExactSynonym "Deforolimus" @default.
- NCIT_C49061 hasExactSynonym "MK-8669" @default.
- NCIT_C49061 hasExactSynonym "RIDAFOROLIMUS" @default.
- NCIT_C49061 hasExactSynonym "Rapamycin, 42-(dimethylphosphinate)" @default.
- NCIT_C49061 hasExactSynonym "Ridaforolimus" @default.
- NCIT_C49061 hasExactSynonym "ridaforolimus" @default.
- NCIT_C49061 inSubset NCIT_C116977 @default.
- NCIT_C49061 inSubset NCIT_C116978 @default.
- NCIT_C49061 inSubset NCIT_C128784 @default.
- NCIT_C49061 inSubset NCIT_C157711 @default.
- NCIT_C49061 inSubset NCIT_C157712 @default.
- NCIT_C49061 inSubset NCIT_C176424 @default.
- NCIT_C49061 inSubset NCIT_C177537 @default.
- NCIT_C49061 inSubset NCIT_C63923 @default.
- NCIT_C49061 type Class @default.
- NCIT_C49061 isDefinedBy ncit.owl @default.
- NCIT_C49061 label "Ridaforolimus" @default.
- NCIT_C49061 subClassOf B0bbc735127d7bbf124a8f3be8bd6ec48 @default.
- NCIT_C49061 subClassOf B529d5d5252d49e255ebd4afe5e7ed180 @default.
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- NCIT_C49061 subClassOf NCIT_C1404 @default.
- NCIT_C49061 subClassOf NCIT_C163758 @default.
- NCIT_C49061 subClassOf NCIT_C1908 @default.
- NCIT_C49061 subClassOf NCIT_C1909 @default.
- NCIT_C49061 subClassOf NCIT_C2201 @default.
- NCIT_C49061 subClassOf NCIT_C274 @default.
- NCIT_C49061 subClassOf NCIT_C471 @default.
- NCIT_C49061 subClassOf NCIT_C49061 @default.
- NCIT_C49061 subClassOf NCIT_C61074 @default.