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- NCIT_C49091 IAO_0000115 "A small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor cell populations. Plk1, a serine/threonine-protein kinase, is a key regulator of multiple processes fundamental to mitosis and cell division." @default.
- NCIT_C49091 NCIT_A32 NCIT_C1909 @default.
- NCIT_C49091 NCIT_A7 NCIT_C17911 @default.
- NCIT_C49091 NCIT_NHC0 "C49091" @default.
- NCIT_C49091 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C49091 NCIT_P107 "Plk1 Inhibitor BI 2536" @default.
- NCIT_C49091 NCIT_P108 "Plk1 Inhibitor BI 2536" @default.
- NCIT_C49091 NCIT_P207 "C1706888" @default.
- NCIT_C49091 NCIT_P210 "755038-02-9" @default.
- NCIT_C49091 NCIT_P319 "4LJG22T9C6" @default.
- NCIT_C49091 NCIT_P322 "CTRP" @default.
- NCIT_C49091 NCIT_P322 "FDA" @default.
- NCIT_C49091 NCIT_P322 "GDC" @default.
- NCIT_C49091 NCIT_P325 "A substance being studied in the treatment of cancer. It prevents cells from dividing and may block the growth of some tumors. It is a type of mitotic inhibitor." @default.
- NCIT_C49091 NCIT_P329 "452943" @default.
- NCIT_C49091 NCIT_P330 "452943" @default.
- NCIT_C49091 NCIT_P366 "BI_2536" @default.
- NCIT_C49091 NCIT_P375 "Plk1 Inhibitor BI 2536" @default.
- NCIT_C49091 NCIT_P399 "452943" @default.
- NCIT_C49091 normalizedInformationContent "100" @default.
- NCIT_C49091 referenceCount "1" @default.
- NCIT_C49091 hasExactSynonym "BI 2536" @default.
- NCIT_C49091 hasExactSynonym "BI-2536" @default.
- NCIT_C49091 hasExactSynonym "Plk1 Inhibitor BI 2536" @default.
- NCIT_C49091 inSubset NCIT_C116977 @default.
- NCIT_C49091 inSubset NCIT_C116978 @default.
- NCIT_C49091 inSubset NCIT_C128784 @default.
- NCIT_C49091 inSubset NCIT_C157711 @default.
- NCIT_C49091 inSubset NCIT_C157712 @default.
- NCIT_C49091 inSubset NCIT_C176424 @default.
- NCIT_C49091 inSubset NCIT_C177537 @default.
- NCIT_C49091 inSubset NCIT_C63923 @default.
- NCIT_C49091 type Class @default.
- NCIT_C49091 isDefinedBy ncit.owl @default.
- NCIT_C49091 label "Plk1 Inhibitor BI 2536" @default.
- NCIT_C49091 subClassOf NCIT_C129824 @default.
- NCIT_C49091 subClassOf NCIT_C129825 @default.
- NCIT_C49091 subClassOf NCIT_C1404 @default.
- NCIT_C49091 subClassOf NCIT_C177899 @default.
- NCIT_C49091 subClassOf NCIT_C1908 @default.
- NCIT_C49091 subClassOf NCIT_C1909 @default.
- NCIT_C49091 subClassOf NCIT_C2189 @default.
- NCIT_C49091 subClassOf NCIT_C274 @default.
- NCIT_C49091 subClassOf NCIT_C471 @default.
- NCIT_C49091 subClassOf NCIT_C49091 @default.
- NCIT_C49091 subClassOf NCIT_C61074 @default.