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- NCIT_C49356 IAO_0000115 "Human BIRC3 wild-type allele is located in the vicinity of 11q25 and is approximately 14 kb in length. This allele, which encodes baculoviral IAP repeat-containing protein 3, is involved in apoptotic inhibition by serum deprivation." @default.
- NCIT_C49356 NCIT_NHC0 "C49356" @default.
- NCIT_C49356 NCIT_P100 "601721" @default.
- NCIT_C49356 NCIT_P102 "NM_001165" @default.
- NCIT_C49356 NCIT_P106 "Gene or Genome" @default.
- NCIT_C49356 NCIT_P107 "BIRC3 wt Allele" @default.
- NCIT_C49356 NCIT_P108 "BIRC3 wt Allele" @default.
- NCIT_C49356 NCIT_P207 "C1705378" @default.
- NCIT_C49356 NCIT_P211 "anti-apoptosis" @default.
- NCIT_C49356 NCIT_P211 "apoptosis inhibitor activity" @default.
- NCIT_C49356 NCIT_P211 "cell surface receptor linked signal transduction" @default.
- NCIT_C49356 NCIT_P321 "330" @default.
- NCIT_C49356 NCIT_P322 "CTRP" @default.
- NCIT_C49356 NCIT_P366 "BIRC3_wt_Allele" @default.
- NCIT_C49356 NCIT_P96 "Baculoviral IAP Repeat-Containing Protein 3" @default.
- NCIT_C49356 NCIT_P98 "BIRC3 inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring-type zinc finger domain while the Zn binding domain is involved in protein-protein interactions in caspase inhibition and spindle assembly. BIRC3 is present in many fetal and adult tissues and mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes." @default.
- NCIT_C49356 NCIT_P98 "The BIRC3 gene is involved in a chromosomal translocation t(11;18)(q21;q21) with the MALT1 gene in mucosa-associated lymphoid tissue lymphomas." @default.
- NCIT_C49356 NCIT_R130 NCIT_C17132 @default.
- NCIT_C49356 NCIT_R130 NCIT_C19779 @default.
- NCIT_C49356 NCIT_R130 NCIT_C20633 @default.
- NCIT_C49356 NCIT_R130 NCIT_C39014 @default.
- NCIT_C49356 NCIT_R130 NCIT_C39106 @default.
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- NCIT_C49356 NCIT_R130 NCIT_C39234 @default.
- NCIT_C49356 NCIT_R130 NCIT_C39699 @default.
- NCIT_C49356 NCIT_R145 NCIT_C12219 @default.
- NCIT_C49356 NCIT_R145 NCIT_C21599 @default.
- NCIT_C49356 NCIT_R145 NCIT_C40342 @default.
- NCIT_C49356 NCIT_R145 NCIT_C41778 @default.
- NCIT_C49356 NCIT_R145 NCIT_C42312 @default.
- NCIT_C49356 NCIT_R145 NCIT_C64389 @default.
- NCIT_C49356 NCIT_R37 NCIT_C17557 @default.
- NCIT_C49356 NCIT_R37 NCIT_C17710 @default.
- NCIT_C49356 NCIT_R37 NCIT_C17828 @default.
- NCIT_C49356 NCIT_R37 NCIT_C18219 @default.
- NCIT_C49356 NCIT_R37 NCIT_C18469 @default.
- NCIT_C49356 NCIT_R37 NCIT_C19932 @default.
- NCIT_C49356 NCIT_R37 NCIT_C19986 @default.
- NCIT_C49356 NCIT_R37 NCIT_C20480 @default.
- NCIT_C49356 NCIT_R37 NCIT_C40727 @default.
- NCIT_C49356 NCIT_R37 NCIT_C41515 @default.
- NCIT_C49356 NCIT_R37 NCIT_C51037 @default.
- NCIT_C49356 NCIT_R40 NCIT_C12219 @default.
- NCIT_C49356 NCIT_R40 NCIT_C13282 @default.
- NCIT_C49356 NCIT_R40 NCIT_C13377 @default.
- NCIT_C49356 NCIT_R40 NCIT_C13432 @default.
- NCIT_C49356 NCIT_R40 NCIT_C13446 @default.
- NCIT_C49356 NCIT_R40 NCIT_C13754 @default.
- NCIT_C49356 NCIT_R40 NCIT_C14135 @default.
- NCIT_C49356 NCIT_R40 NCIT_C32221 @default.
- NCIT_C49356 NCIT_R40 NCIT_C34070 @default.
- NCIT_C49356 NCIT_R41 NCIT_C14182 @default.
- NCIT_C49356 NCIT_R41 NCIT_C14225 @default.
- NCIT_C49356 NCIT_R41 NCIT_C14234 @default.
- NCIT_C49356 NCIT_R41 NCIT_C14250 @default.
- NCIT_C49356 NCIT_R41 NCIT_C14262 @default.
- NCIT_C49356 NCIT_R41 NCIT_C14282 @default.
- NCIT_C49356 NCIT_R41 NCIT_C25796 @default.
- NCIT_C49356 NCIT_R41 NCIT_C79740 @default.
- NCIT_C49356 normalizedInformationContent "100" @default.
- NCIT_C49356 referenceCount "1" @default.
- NCIT_C49356 hasExactSynonym "API2" @default.
- NCIT_C49356 hasExactSynonym "Apoptosis Inhibitor 2 Gene" @default.
- NCIT_C49356 hasExactSynonym "BIRC3 wt Allele" @default.
- NCIT_C49356 hasExactSynonym "Baculoviral IAP Repeat Containing 3 wt Allele" @default.
- NCIT_C49356 hasExactSynonym "Baculoviral IAP Repeat-Containing 3 Gene" @default.
- NCIT_C49356 hasExactSynonym "Baculoviral IAP Repeat-Containing Protein 3 Gene" @default.
- NCIT_C49356 hasExactSynonym "CIAP2" @default.
- NCIT_C49356 hasExactSynonym "HIAP1" @default.
- NCIT_C49356 hasExactSynonym "IAP Homolog C Gene" @default.
- NCIT_C49356 hasExactSynonym "MALT2" @default.
- NCIT_C49356 hasExactSynonym "MIHC" @default.
- NCIT_C49356 hasExactSynonym "Mammalian IAP Homolog C Gene" @default.
- NCIT_C49356 hasExactSynonym "RNF49" @default.
- NCIT_C49356 hasExactSynonym "c-IAP2" @default.
- NCIT_C49356 hasExactSynonym "cIAP2" @default.
- NCIT_C49356 hasExactSynonym "hiap-1" @default.
- NCIT_C49356 inSubset NCIT_C116977 @default.
- NCIT_C49356 inSubset NCIT_C142799 @default.
- NCIT_C49356 inSubset NCIT_C142800 @default.
- NCIT_C49356 type Class @default.
- NCIT_C49356 isDefinedBy ncit.owl @default.
- NCIT_C49356 label "BIRC3 wt Allele" @default.
- NCIT_C49356 subClassOf NCIT_C16612 @default.
- NCIT_C49356 subClassOf NCIT_C20347 @default.
- NCIT_C49356 subClassOf NCIT_C20356 @default.
- NCIT_C49356 subClassOf NCIT_C20462 @default.
- NCIT_C49356 subClassOf NCIT_C20938 @default.
- NCIT_C49356 subClassOf NCIT_C49356 @default.
- NCIT_C49356 equivalentClass B0b26e4bb9b5623265e332cd066851441 @default.
- NCIT_C49356 equivalentClass Bb3cdf9bd5c7f74c8790138f888b747d6 @default.