Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C49510> ?p ?o ?g. }
- NCIT_C49510 IAO_0000115 "Human CDKN1C wild-type allele located in the vicinity of 11p15.5 and is approximately 2 kb in length. This allele, which encodes cyclin-dependent kinase inhibitor 1C protein, plays a negative role in the regulation of cellular proliferation by inhibiting several G1 cyclin/Cdk complexes. Mutations of the gene, which generates variant alleles have been implicated in both sporadic cancers and Beckwith-Wiedemann syndrome, suggesting that it is a tumor suppressor candidate." @default.
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- NCIT_C49510 NCIT_P211 "G1 phase of mitotic cell cycle" @default.
- NCIT_C49510 NCIT_P211 "cell cycle arrest" @default.
- NCIT_C49510 NCIT_P211 "cyclin-dependent protein kinase inhibitor activity" @default.
- NCIT_C49510 NCIT_P211 "negative regulation of cell proliferation" @default.
- NCIT_C49510 NCIT_P211 "regulation of CDK activity" @default.
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- NCIT_C49510 hasExactSynonym "BWCR" @default.
- NCIT_C49510 hasExactSynonym "BWS" @default.
- NCIT_C49510 hasExactSynonym "CDKN1C wt Allele" @default.
- NCIT_C49510 hasExactSynonym "Cyclin-Dependent Kinase Inhibitor 1C wt Allele" @default.
- NCIT_C49510 hasExactSynonym "KIP2 Gene" @default.
- NCIT_C49510 hasExactSynonym "KIP2" @default.
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