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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C49523> ?p ?o ?g. }

• NCIT_C49523 IAO_0000115 "Human CCND2 wild-type allele is located in the vicinity of 12p13.32 and is approximately 32 kb in length. This allele, which encodes G1/S-specific cyclin D2 protein, plays a role in cell cycle regulation. Methylation of the gene generates allelic variants that are implicated in the pathogenesis of several cancers." @default.
• NCIT_C49523 NCIT_NHC0 "C49523" @default.
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• NCIT_C49523 NCIT_P102 "NM_001759" @default.
• NCIT_C49523 NCIT_P106 "Gene or Genome" @default.
• NCIT_C49523 NCIT_P107 "CCND2 wt Allele" @default.
• NCIT_C49523 NCIT_P108 "CCND2 wt Allele" @default.
• NCIT_C49523 NCIT_P207 "C1707087" @default.
• NCIT_C49523 NCIT_P321 "894" @default.
• NCIT_C49523 NCIT_P322 "CTRP" @default.
• NCIT_C49523 NCIT_P366 "CCND2_wt_Allele" @default.
• NCIT_C49523 NCIT_P96 "Cyclin-D2" @default.
• NCIT_C49523 NCIT_P98 "Knockout studies of the homologous gene in mouse suggest that the essential roles of this gene are in ovarian granulosa and germ cell proliferation. High levels of CCND2 expression were observed in ovarian and testicular tumors. Methylation of the CCND2 promoter region results in decreased cyclin D2 protein levels and has been detected in both gastric and prostate cancers in humans. Conversely, cyclin D2 is overexpressed in human brain tumors, specifically astrocytomas and glioblastomas." @default.
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• NCIT_C49523 normalizedInformationContent "100" @default.
• NCIT_C49523 referenceCount "1" @default.
• NCIT_C49523 hasExactSynonym "CCND2 wt Allele" @default.
• NCIT_C49523 hasExactSynonym "Cyclin D2 wt Allele" @default.
• NCIT_C49523 hasExactSynonym "KIAK0002" @default.
• NCIT_C49523 hasExactSynonym "MPPH3" @default.
• NCIT_C49523 inSubset NCIT_C116977 @default.

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