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- NCIT_C50936 IAO_0000115 "Human TDO2 wild-type allele is located within 4q31-q32 and is approximately 17 kb in length. This allele, which encodes tryptophan 2,3-dioxygenase protein, is involved in the metabolic breakdown of tryptamine and its derivatives such as tryptophan, 5-hydroxytryptophan, and serotonin." @default.
- NCIT_C50936 NCIT_NHC0 "C50936" @default.
- NCIT_C50936 NCIT_P100 "191070" @default.
- NCIT_C50936 NCIT_P102 "NM_005651" @default.
- NCIT_C50936 NCIT_P106 "Gene or Genome" @default.
- NCIT_C50936 NCIT_P107 "TDO2 wt Allele" @default.
- NCIT_C50936 NCIT_P108 "TDO2 wt Allele" @default.
- NCIT_C50936 NCIT_P207 "C1706150" @default.
- NCIT_C50936 NCIT_P321 "6999" @default.
- NCIT_C50936 NCIT_P322 "CTRP" @default.
- NCIT_C50936 NCIT_P366 "TDO2_wt_Allele" @default.
- NCIT_C50936 NCIT_P96 "Tryptophanase" @default.
- NCIT_C50936 NCIT_P98 "Allelic variants of the TDO2 gene have been identified that result in protein products which exhibit altered enzymatic activity. Certain polymorphisms are associated with alcoholism, attention deficit hyperactivity disorder, drug dependence and Tourette syndrome. However, the role of the TDO2 gene in addiction and mental disorders remains to be elucidated." @default.
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- NCIT_C50936 hasExactSynonym "TDO2 wt Allele" @default.
- NCIT_C50936 hasExactSynonym "TPH2" @default.
- NCIT_C50936 hasExactSynonym "Tryptophan 2,3-Dioxygenase wt Allele" @default.
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- NCIT_C50936 type Class @default.
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- NCIT_C50936 label "TDO2 wt Allele" @default.
- NCIT_C50936 subClassOf NCIT_C16612 @default.
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