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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C51061> ?p ?o ?g. }

Showing items 1 to 100 of ±172 with 100 items per page.

NCIT_C51061 IAO_0000115 "Human ABL1 wild-type allele is located in the vicinity of 9q34.1 and is approximately 173 kb in length. This allele, which encodes proto-oncogene tyrosine-protein kinase ABL1 protein, plays a role in cell cycle regulation and ribosomal biogenesis. The ABL1 gene is translocated in chronic myelogeneous leukemia, acute lymphoblastic leukemia and, in rare cases, acute myelogenous leukemia." @default.
NCIT_C51061 NCIT_NHC0 "C51061" @default.
NCIT_C51061 NCIT_P100 "189980" @default.
NCIT_C51061 NCIT_P102 "NM_007313" @default.
NCIT_C51061 NCIT_P106 "Gene or Genome" @default.
NCIT_C51061 NCIT_P107 "ABL1 wt Allele" @default.
NCIT_C51061 NCIT_P108 "ABL1 wt Allele" @default.
NCIT_C51061 NCIT_P207 "C1704928" @default.
NCIT_C51061 NCIT_P211 "DNA binding" @default.
NCIT_C51061 NCIT_P211 "DNA damage response, signal transduction resulting in induction of apoptosis" @default.
NCIT_C51061 NCIT_P211 "S-specific transcription in mitotic cell cycle" @default.
NCIT_C51061 NCIT_P211 "biological_process unknown" @default.
NCIT_C51061 NCIT_P211 "cellular_component unknown" @default.
NCIT_C51061 NCIT_P211 "mismatch repair" @default.
NCIT_C51061 NCIT_P211 "molecular_function unknown" @default.
NCIT_C51061 NCIT_P211 "nucleus" @default.
NCIT_C51061 NCIT_P211 "protein modification" @default.
NCIT_C51061 NCIT_P211 "protein tyrosine kinase activity" @default.
NCIT_C51061 NCIT_P211 "regulation of cell cycle" @default.
NCIT_C51061 NCIT_P211 "regulation of transcription, DNA-dependent" @default.
NCIT_C51061 NCIT_P321 "25" @default.
NCIT_C51061 NCIT_P322 "CTRP" @default.
NCIT_C51061 NCIT_P325 "An enzyme that is involved in many cell processes, such as cell division. The gene for c-ABL is on chromosome 9. In most patients with chronic myelogenous leukemia (CML), the part of chromosome 9 with c-ABL has broken off and traded places with part of chromosome 22 to form the BCR-ABL fusion gene." @default.
NCIT_C51061 NCIT_P366 "ABL1_wt_Allele" @default.
NCIT_C51061 NCIT_P96 "ABL1 Tyrosine Kinase" @default.
NCIT_C51061 NCIT_P98 "In some types of leukemia, the ABL1 gene forms an oncogenic BCR-ABL fusion gene via a t(9;22)(q34;q11) translocation. Certain allelic variants of the ABL1 gene detected in leukemia patients confer resistance to the chemotherapeutic agent imatinib mesylate. The ABL1 gene undergoes alternative splicing to yield two protein isoforms. Alternatively-spliced exon 1a encodes a nuclear ABL1 protein isoform that enhances target gene transcription. Alternatively spliced exon 1b encodes a myristylated, plasma membrane-associated ABL1 protein isoform." @default.
NCIT_C51061 NCIT_R130 NCIT_C17132 @default.
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NCIT_C51061 NCIT_R130 NCIT_C19779 @default.
NCIT_C51061 NCIT_R130 NCIT_C20633 @default.
NCIT_C51061 NCIT_R130 NCIT_C38794 @default.
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NCIT_C51061 NCIT_R130 NCIT_C39086 @default.
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NCIT_C51061 NCIT_R130 NCIT_C91436 @default.
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NCIT_C51061 NCIT_R130 NCIT_C91514 @default.
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NCIT_C51061 NCIT_R175 NCIT_C4345 @default.
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NCIT_C51061 NCIT_R175 NCIT_C7055 @default.
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NCIT_C51061 NCIT_R175 NCIT_C7464 @default.
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NCIT_C51061 NCIT_R37 NCIT_C16397 @default.
NCIT_C51061 NCIT_R37 NCIT_C16399 @default.
NCIT_C51061 NCIT_R37 NCIT_C16402 @default.
NCIT_C51061 NCIT_R37 NCIT_C16674 @default.
NCIT_C51061 NCIT_R37 NCIT_C16983 @default.