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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C51197> ?p ?o ?g. }

• NCIT_C51197 IAO_0000115 "Human CHEK2 wild-type allele is located in the vicinity of 22q12.1 and is approximately 57 kb in length. This allele, which encodes serine/threonine-protein kinase Chk2 protein, is involved in prevention of entry into mitosis and induction of G1 checkpoint arrest in response to DNA damage. Certain allelic variants of the CHEK2 gene that encode protein products with reduced or abolished activity are associated with Li-Fraumeni syndrome 2. Heritable alterations in this gene also confer susceptibility to breast, colorectal and prostate cancers." @default.
• NCIT_C51197 NCIT_NHC0 "C51197" @default.
• NCIT_C51197 NCIT_P100 "604373" @default.
• NCIT_C51197 NCIT_P102 "NM_007194" @default.
• NCIT_C51197 NCIT_P106 "Gene or Genome" @default.
• NCIT_C51197 NCIT_P107 "CHEK2 wt Allele" @default.
• NCIT_C51197 NCIT_P108 "CHEK2 wt Allele" @default.
• NCIT_C51197 NCIT_P207 "C1706047" @default.
• NCIT_C51197 NCIT_P321 "11200" @default.
• NCIT_C51197 NCIT_P322 "CTRP" @default.
• NCIT_C51197 NCIT_P366 "CHEK2_wt_Allele" @default.
• NCIT_C51197 NCIT_P96 "Serine/Threonine-Protein Kinase CHK2" @default.
• NCIT_C51197 NCIT_P98 "The CHEK2 gene is a putative tumor suppressor gene. Somatic mutations in this gene are associated with osteosarcoma and prostate cancer." @default.
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