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- NCIT_C51516 IAO_0000115 "Human NRG2 wild-type allele is located within 5q23-q33 and is approximately 195 kb in length. This allele, which encodes pro-neuregulin-2, membrane-bound isoform protein, plays a role in the induction of growth and differentiation for several types of cells." @default.
- NCIT_C51516 NCIT_NHC0 "C51516" @default.
- NCIT_C51516 NCIT_P100 "603818" @default.
- NCIT_C51516 NCIT_P102 "NM_004883" @default.
- NCIT_C51516 NCIT_P106 "Gene or Genome" @default.
- NCIT_C51516 NCIT_P107 "NRG2 wt Allele" @default.
- NCIT_C51516 NCIT_P108 "NRG2 wt Allele" @default.
- NCIT_C51516 NCIT_P207 "C1705131" @default.
- NCIT_C51516 NCIT_P211 "anti-apoptosis" @default.
- NCIT_C51516 NCIT_P211 "cell-cell signaling" @default.
- NCIT_C51516 NCIT_P211 "development" @default.
- NCIT_C51516 NCIT_P211 "receptor binding" @default.
- NCIT_C51516 NCIT_P211 "signal transduction" @default.
- NCIT_C51516 NCIT_P321 "9542" @default.
- NCIT_C51516 NCIT_P322 "CTRP" @default.
- NCIT_C51516 NCIT_P366 "NRG2_wt_Allele" @default.
- NCIT_C51516 NCIT_P96 "Neuregulin 2" @default.
- NCIT_C51516 NCIT_P98 "Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease." @default.
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- NCIT_C51516 NCIT_R41 NCIT_C14182 @default.
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- NCIT_C51516 NCIT_R41 NCIT_C14234 @default.
- NCIT_C51516 NCIT_R41 NCIT_C14250 @default.
- NCIT_C51516 NCIT_R41 NCIT_C14262 @default.
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- NCIT_C51516 NCIT_R41 NCIT_C25796 @default.
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- NCIT_C51516 hasExactSynonym "DON-1" @default.
- NCIT_C51516 hasExactSynonym "DON1" @default.
- NCIT_C51516 hasExactSynonym "HRG2" @default.
- NCIT_C51516 hasExactSynonym "NRG2 wt Allele" @default.
- NCIT_C51516 hasExactSynonym "NTAK" @default.
- NCIT_C51516 hasExactSynonym "Neuregulin 2 wt Allele" @default.
- NCIT_C51516 inSubset NCIT_C116977 @default.
- NCIT_C51516 inSubset NCIT_C142799 @default.
- NCIT_C51516 inSubset NCIT_C142800 @default.
- NCIT_C51516 type Class @default.
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- NCIT_C51516 label "NRG2 wt Allele" @default.
- NCIT_C51516 subClassOf NCIT_C16612 @default.
- NCIT_C51516 subClassOf NCIT_C21344 @default.
- NCIT_C51516 subClassOf NCIT_C24641 @default.
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