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- NCIT_C516 IAO_0000115 "A glycosphingolipid antigen expressed by a variety of human cancer cells. GM2 containing vaccines have been shown to elicit antibodies production in melanoma patients without deleterious effects associated with an immune response to GM2. Mutations in at least 1 of 3 recessive genes: HEXA, HEXB, and GM2A cause defects in GM2 catabolism, leading to lysosomal lipid storage disorders that manifest primarily as neurodegenerative diseases, including Tay-Sachs and Sandhoff Disease." @default.
- NCIT_C516 NCIT_A32 NCIT_C1909 @default.
- NCIT_C516 NCIT_NHC0 "C516" @default.
- NCIT_C516 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C516 NCIT_P106 "Organic Chemical" @default.
- NCIT_C516 NCIT_P107 "Ganglioside GM2" @default.
- NCIT_C516 NCIT_P108 "Ganglioside GM2" @default.
- NCIT_C516 NCIT_P207 "C0016896" @default.
- NCIT_C516 NCIT_P210 "19600-01-2" @default.
- NCIT_C516 NCIT_P322 "CDISC" @default.
- NCIT_C516 NCIT_P322 "CTRP" @default.
- NCIT_C516 NCIT_P322 "GDC" @default.
- NCIT_C516 NCIT_P325 "A sialic acid-containing glycosphingolipid antigen and a component of the cell plasma membrane that modulates cell signal transduction, with a designation of GM2. It can be considered as an autoantigen and is commonly associated with autoimmune neuropathies such as Guillain-Barre syndrome and multiple sclerosis." @default.
- NCIT_C516 NCIT_P329 "40785" @default.
- NCIT_C516 NCIT_P330 "40785" @default.
- NCIT_C516 NCIT_P366 "Ganglioside_GM2" @default.
- NCIT_C516 NCIT_P375 "Ganglioside GM2" @default.
- NCIT_C516 NCIT_P399 "40785" @default.
- NCIT_C516 normalizedInformationContent "100" @default.
- NCIT_C516 referenceCount "1" @default.
- NCIT_C516 hasExactSynonym "GANGLIOSIDE GM2" @default.
- NCIT_C516 hasExactSynonym "GM2 ganglioside" @default.
- NCIT_C516 hasExactSynonym "Ganglioside GM2" @default.
- NCIT_C516 inSubset NCIT_C116977 @default.
- NCIT_C516 inSubset NCIT_C128784 @default.
- NCIT_C516 inSubset NCIT_C142799 @default.
- NCIT_C516 inSubset NCIT_C157711 @default.
- NCIT_C516 inSubset NCIT_C157712 @default.
- NCIT_C516 inSubset NCIT_C176424 @default.
- NCIT_C516 inSubset NCIT_C177537 @default.
- NCIT_C516 inSubset NCIT_C181169 @default.
- NCIT_C516 inSubset NCIT_C61410 @default.
- NCIT_C516 inSubset NCIT_C66830 @default.
- NCIT_C516 type Class @default.
- NCIT_C516 isDefinedBy ncit.owl @default.
- NCIT_C516 label "Ganglioside GM2" @default.
- NCIT_C516 subClassOf NCIT_C1908 @default.
- NCIT_C516 subClassOf NCIT_C1909 @default.
- NCIT_C516 subClassOf NCIT_C1913 @default.
- NCIT_C516 subClassOf NCIT_C268 @default.
- NCIT_C516 subClassOf NCIT_C307 @default.
- NCIT_C516 subClassOf NCIT_C344 @default.
- NCIT_C516 subClassOf NCIT_C516 @default.
- NCIT_C516 subClassOf NCIT_C518 @default.
- NCIT_C516 subClassOf NCIT_C616 @default.
- NCIT_C516 subClassOf NCIT_C718 @default.
- NCIT_C516 subClassOf NCIT_C912 @default.