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- NCIT_C519 IAO_0000115 "A broad-spectrum aminoglycoside antibiotic produced by fermentation of Micromonospora purpurea or M. echinospora. Gentamicin is an antibiotic complex consisting of four major (C1, C1a, C2, and C2a) and several minor components. This agent irreversibly binds to the bacterial 30S ribosomal subunit. Specifically, this antibiotic is lodged between 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex, misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses." @default.
- NCIT_C519 NCIT_A5 NCIT_C65803 @default.
- NCIT_C519 NCIT_NHC0 "C519" @default.
- NCIT_C519 NCIT_P106 "Antibiotic" @default.
- NCIT_C519 NCIT_P106 "Organic Chemical" @default.
- NCIT_C519 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C519 NCIT_P107 "Gentamicin" @default.
- NCIT_C519 NCIT_P108 "Gentamicin" @default.
- NCIT_C519 NCIT_P171 "15690437" @default.
- NCIT_C519 NCIT_P207 "C0017436" @default.
- NCIT_C519 NCIT_P210 "1403-66-3" @default.
- NCIT_C519 NCIT_P319 "T6Z9V48IKG" @default.
- NCIT_C519 NCIT_P322 "CTRP" @default.
- NCIT_C519 NCIT_P322 "FDA" @default.
- NCIT_C519 NCIT_P329 "39250" @default.
- NCIT_C519 NCIT_P330 "39250" @default.
- NCIT_C519 NCIT_P366 "Gentamicin" @default.
- NCIT_C519 NCIT_P368 "CHEBI:17833" @default.
- NCIT_C519 NCIT_P399 "39250" @default.
- NCIT_C519 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C519 referenceCount "3" @default.
- NCIT_C519 hasExactSynonym "GENTAMICIN" @default.
- NCIT_C519 hasExactSynonym "Garamicin" @default.
- NCIT_C519 hasExactSynonym "Garamycin" @default.
- NCIT_C519 hasExactSynonym "Genoptic S.O.P." @default.
- NCIT_C519 hasExactSynonym "Genoptic" @default.
- NCIT_C519 hasExactSynonym "Gentamicin" @default.
- NCIT_C519 hasExactSynonym "Gentamycin Complex" @default.
- NCIT_C519 hasExactSynonym "Gentamycin" @default.
- NCIT_C519 hasExactSynonym "U-Gencin" @default.
- NCIT_C519 inSubset NCIT_C116977 @default.
- NCIT_C519 inSubset NCIT_C116978 @default.
- NCIT_C519 inSubset NCIT_C176424 @default.
- NCIT_C519 inSubset NCIT_C63923 @default.
- NCIT_C519 type Class @default.
- NCIT_C519 isDefinedBy ncit.owl @default.
- NCIT_C519 label "Gentamicin" @default.
- NCIT_C519 subClassOf NCIT_C1908 @default.
- NCIT_C519 subClassOf NCIT_C1909 @default.
- NCIT_C519 subClassOf NCIT_C2363 @default.
- NCIT_C519 subClassOf NCIT_C254 @default.
- NCIT_C519 subClassOf NCIT_C258 @default.
- NCIT_C519 subClassOf NCIT_C519 @default.
- NCIT_C519 subClassOf NCIT_C784 @default.