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- NCIT_C52074 IAO_0000115 "Human HMGA1 wild-type allele is located within 6p21 and is approximately 9 kb in length. This allele, which encodes high mobility group protein HMG-I/HMG-Y, is involved in chromatin remodeling, DNA-dependent transcriptional regulation and inhibition of tumor suppressor p53 protein-dependent apoptosis. The HMGA1 gene is overexpressed in certain types of cancer including breast carcinoma, colorectal cancer, non-small-cell lung carcinoma, epithelial ovarian carcinoma and thyroid cancer." @default.
- NCIT_C52074 NCIT_NHC0 "C52074" @default.
- NCIT_C52074 NCIT_P100 "600701" @default.
- NCIT_C52074 NCIT_P102 "NM_002131" @default.
- NCIT_C52074 NCIT_P106 "Gene or Genome" @default.
- NCIT_C52074 NCIT_P108 "HMGA1 wt Allele" @default.
- NCIT_C52074 NCIT_P207 "C1708280" @default.
- NCIT_C52074 NCIT_P211 "AT DNA binding" @default.
- NCIT_C52074 NCIT_P211 "DNA binding" @default.
- NCIT_C52074 NCIT_P211 "regulation of transcription, DNA-dependent" @default.
- NCIT_C52074 NCIT_P321 "3159" @default.
- NCIT_C52074 NCIT_P366 "HMGA1_wt_Allele" @default.
- NCIT_C52074 NCIT_P96 "HMGA1a" @default.
- NCIT_C52074 NCIT_P96 "HMGA1b" @default.
- NCIT_C52074 NCIT_P96 "HMGA1c" @default.
- NCIT_C52074 NCIT_P98 "This gene may play a role in both nucleosome phasing and processing of the 3' end of mRNA transcripts. Defects in the HMGA1 gene are suggested to cause both decreased insulin receptor expression and induction of insulin resistance." @default.
- NCIT_C52074 NCIT_R145 NCIT_C12219 @default.
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- NCIT_C52074 NCIT_R37 NCIT_C16397 @default.
- NCIT_C52074 NCIT_R37 NCIT_C17208 @default.
- NCIT_C52074 NCIT_R37 NCIT_C17710 @default.
- NCIT_C52074 NCIT_R37 NCIT_C17828 @default.
- NCIT_C52074 NCIT_R37 NCIT_C17930 @default.
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- NCIT_C52074 NCIT_R37 NCIT_C18219 @default.
- NCIT_C52074 NCIT_R37 NCIT_C18597 @default.
- NCIT_C52074 NCIT_R37 NCIT_C18839 @default.
- NCIT_C52074 NCIT_R37 NCIT_C19077 @default.
- NCIT_C52074 NCIT_R37 NCIT_C19986 @default.
- NCIT_C52074 NCIT_R37 NCIT_C20480 @default.
- NCIT_C52074 NCIT_R37 NCIT_C21049 @default.
- NCIT_C52074 NCIT_R37 NCIT_C21050 @default.
- NCIT_C52074 NCIT_R37 NCIT_C21102 @default.
- NCIT_C52074 NCIT_R37 NCIT_C21124 @default.
- NCIT_C52074 NCIT_R37 NCIT_C28498 @default.
- NCIT_C52074 NCIT_R37 NCIT_C28614 @default.
- NCIT_C52074 NCIT_R37 NCIT_C28683 @default.
- NCIT_C52074 NCIT_R37 NCIT_C40523 @default.
- NCIT_C52074 NCIT_R40 NCIT_C12219 @default.
- NCIT_C52074 NCIT_R40 NCIT_C13282 @default.
- NCIT_C52074 NCIT_R40 NCIT_C13377 @default.
- NCIT_C52074 NCIT_R40 NCIT_C13432 @default.
- NCIT_C52074 NCIT_R40 NCIT_C13446 @default.
- NCIT_C52074 NCIT_R40 NCIT_C13603 @default.
- NCIT_C52074 NCIT_R40 NCIT_C14135 @default.
- NCIT_C52074 NCIT_R40 NCIT_C32221 @default.
- NCIT_C52074 NCIT_R40 NCIT_C34070 @default.
- NCIT_C52074 NCIT_R41 NCIT_C14182 @default.
- NCIT_C52074 NCIT_R41 NCIT_C14225 @default.
- NCIT_C52074 NCIT_R41 NCIT_C14234 @default.
- NCIT_C52074 NCIT_R41 NCIT_C14250 @default.
- NCIT_C52074 NCIT_R41 NCIT_C14262 @default.
- NCIT_C52074 NCIT_R41 NCIT_C14282 @default.
- NCIT_C52074 NCIT_R41 NCIT_C25796 @default.
- NCIT_C52074 NCIT_R41 NCIT_C79740 @default.
- NCIT_C52074 normalizedInformationContent "100" @default.
- NCIT_C52074 referenceCount "1" @default.
- NCIT_C52074 hasExactSynonym "HMG-I(Y) Gene" @default.
- NCIT_C52074 hasExactSynonym "HMG-R Gene" @default.
- NCIT_C52074 hasExactSynonym "HMG1A1" @default.
- NCIT_C52074 hasExactSynonym "HMGA1 wt Allele" @default.
- NCIT_C52074 hasExactSynonym "HMGIY Gene" @default.
- NCIT_C52074 hasExactSynonym "High Mobility Group AT-Hook 1 wt Allele" @default.
- NCIT_C52074 hasExactSynonym "High Mobility Group Protein HMG-I/HMG-Y Gene" @default.
- NCIT_C52074 hasExactSynonym "High Mobility Group Protein HMGI-Y Gene" @default.
- NCIT_C52074 hasExactSynonym "High Mobility Group Protein Isoforms I and Y Gene" @default.
- NCIT_C52074 hasExactSynonym "High-Mobility Group (Nonhistone Chromosomal) Protein Isoforms I And Y Gene" @default.
- NCIT_C52074 hasExactSynonym "MGC12816 Gene" @default.
- NCIT_C52074 hasExactSynonym "MGC4242 Gene" @default.
- NCIT_C52074 hasExactSynonym "MGC4854 Gene" @default.
- NCIT_C52074 hasExactSynonym "Nonhistone Chromosomal High-Mobility Group Protein HMG-I/HMG-Y Gene" @default.
- NCIT_C52074 type Class @default.
- NCIT_C52074 isDefinedBy ncit.owl @default.
- NCIT_C52074 label "HMGA1 wt Allele" @default.
- NCIT_C52074 subClassOf NCIT_C16612 @default.
- NCIT_C52074 subClassOf NCIT_C20570 @default.
- NCIT_C52074 subClassOf NCIT_C20573 @default.
- NCIT_C52074 subClassOf NCIT_C20576 @default.
- NCIT_C52074 subClassOf NCIT_C52074 @default.
- NCIT_C52074 subClassOf NCIT_C54362 @default.
- NCIT_C52074 equivalentClass B34ae5ec9b60eeb87d4ca82c8859e9d8e @default.
- NCIT_C52074 equivalentClass B7a502e548c000e97b06caaf8d6a5ea8c @default.