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- NCIT_C52185 IAO_0000115 "A small peptide antagonist of integrin alpha5beta1 with potential antineoplastic activity. ATN-161 selectively binds to and blocks the receptor for integrin alpha5beta1, thereby preventing integrin alpha5beta1 binding. This receptor blockade may result in inhibition of endothelial cell-cell interactions, endothelial cell-matrix interactions, angiogenesis, and tumor progression. Integrin alpha5beta1 is expressed on endothelial cells and plays a crucial role in endothelial cell adhesion and migration." @default.
- NCIT_C52185 NCIT_A32 NCIT_C1909 @default.
- NCIT_C52185 NCIT_NHC0 "C52185" @default.
- NCIT_C52185 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C52185 NCIT_P108 "Alpha V Beta 1 Inhibitor ATN-161" @default.
- NCIT_C52185 NCIT_P207 "C1706674" @default.
- NCIT_C52185 NCIT_P210 "262438-43-7" @default.
- NCIT_C52185 NCIT_P319 "XW0H5LE42K" @default.
- NCIT_C52185 NCIT_P322 "FDA" @default.
- NCIT_C52185 NCIT_P322 "GDC" @default.
- NCIT_C52185 NCIT_P325 "A substance being studied in the treatment of some types of cancer. ATN-161 may prevent the spread of tumor cells and may prevent the growth of new blood vessels that tumors need to grow. It is a type of antiangiogenesis agent." @default.
- NCIT_C52185 NCIT_P329 "459774" @default.
- NCIT_C52185 NCIT_P330 "459774" @default.
- NCIT_C52185 NCIT_P366 "ATN-161" @default.
- NCIT_C52185 NCIT_P375 "Alpha V Beta 1 Inhibitor ATN-161" @default.
- NCIT_C52185 NCIT_P399 "459774" @default.
- NCIT_C52185 normalizedInformationContent "100" @default.
- NCIT_C52185 referenceCount "1" @default.
- NCIT_C52185 hasExactSynonym "ATN-161" @default.
- NCIT_C52185 hasExactSynonym "Alpha V Beta 1 Inhibitor ATN-161" @default.
- NCIT_C52185 inSubset NCIT_C128784 @default.
- NCIT_C52185 inSubset NCIT_C157711 @default.
- NCIT_C52185 inSubset NCIT_C157712 @default.
- NCIT_C52185 inSubset NCIT_C176424 @default.
- NCIT_C52185 inSubset NCIT_C177537 @default.
- NCIT_C52185 inSubset NCIT_C63923 @default.
- NCIT_C52185 type Class @default.
- NCIT_C52185 isDefinedBy ncit.owl @default.
- NCIT_C52185 label "Alpha V Beta 1 Inhibitor ATN-161" @default.
- NCIT_C52185 subClassOf NCIT_C1742 @default.
- NCIT_C52185 subClassOf NCIT_C1908 @default.
- NCIT_C52185 subClassOf NCIT_C1909 @default.
- NCIT_C52185 subClassOf NCIT_C2050 @default.
- NCIT_C52185 subClassOf NCIT_C2144 @default.
- NCIT_C52185 subClassOf NCIT_C274 @default.
- NCIT_C52185 subClassOf NCIT_C52185 @default.