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- NCIT_C52193 IAO_0000115 "A long-acting, hormone-releasing, intrauterine device consisting of a small, T-shaped, polyethylene frame and a reservoired synthetic progesterone with progestational and potential antineoplastic activities. After insertion of this system into the uterus, the device slowly and gradually releases the hormone. Levonorgestrel acts by binding to the progesterone receptor in the nuclei of target cells, resulting in transcription activation and an alteration in protein synthesis. Subsequently, luteinizing hormone (LH) activity and ovulation are suppressed. Levonorgestrel may also exhibit antiproliferative activity in endometrial tissue." @default.
- NCIT_C52193 NCIT_A7 NCIT_C17075 @default.
- NCIT_C52193 NCIT_NHC0 "C52193" @default.
- NCIT_C52193 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C52193 NCIT_P107 "Levonorgestrel-Releasing Intrauterine System" @default.
- NCIT_C52193 NCIT_P108 "Levonorgestrel-Releasing Intrauterine System" @default.
- NCIT_C52193 NCIT_P207 "C0591811" @default.
- NCIT_C52193 NCIT_P322 "CTRP" @default.
- NCIT_C52193 NCIT_P329 "459975" @default.
- NCIT_C52193 NCIT_P330 "459975" @default.
- NCIT_C52193 NCIT_P366 "Levonorgestrel-Releasing_Intrauterine_System" @default.
- NCIT_C52193 NCIT_P399 "459975" @default.
- NCIT_C52193 normalizedInformationContent "100" @default.
- NCIT_C52193 referenceCount "1" @default.
- NCIT_C52193 hasExactSynonym "Levonorgestrel-Releasing Intrauterine System" @default.
- NCIT_C52193 hasExactSynonym "Mirena" @default.
- NCIT_C52193 inSubset NCIT_C116977 @default.
- NCIT_C52193 inSubset NCIT_C116978 @default.
- NCIT_C52193 inSubset NCIT_C176424 @default.
- NCIT_C52193 type Class @default.
- NCIT_C52193 isDefinedBy ncit.owl @default.
- NCIT_C52193 label "Levonorgestrel-Releasing Intrauterine System" @default.
- NCIT_C52193 subClassOf NCIT_C16830 @default.
- NCIT_C52193 subClassOf NCIT_C184790 @default.
- NCIT_C52193 subClassOf NCIT_C19238 @default.
- NCIT_C52193 subClassOf NCIT_C42734 @default.
- NCIT_C52193 subClassOf NCIT_C42771 @default.
- NCIT_C52193 subClassOf NCIT_C52193 @default.
- NCIT_C52193 subClassOf NCIT_C62103 @default.
- NCIT_C52193 subClassOf NCIT_C97325 @default.