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- NCIT_C52355 IAO_0000115 "Human CYP2A6 wild-type allele is located in the vicinity of 19q13.2 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 2A6 protein, plays a role in the hydroxylation of coumarin and oxidation of nicotine. It is also involved in the metabolism of other drugs and xenobiotics. Certain allelic variants of the CYP2A6 gene contribute to the poor metabolizer phenotype. The CYP2A6 wild-type allele is both a determinant of smoking behavior and a susceptibility factor for lung cancer." @default.
- NCIT_C52355 NCIT_NHC0 "C52355" @default.
- NCIT_C52355 NCIT_P100 "122720" @default.
- NCIT_C52355 NCIT_P102 "NM_000762" @default.
- NCIT_C52355 NCIT_P106 "Gene or Genome" @default.
- NCIT_C52355 NCIT_P107 "CYP2A6 wt Allele" @default.
- NCIT_C52355 NCIT_P108 "CYP2A6 wt Allele" @default.
- NCIT_C52355 NCIT_P207 "C1706116" @default.
- NCIT_C52355 NCIT_P321 "1548" @default.
- NCIT_C52355 NCIT_P322 "CTRP" @default.
- NCIT_C52355 NCIT_P366 "CYP2A6_wt_Allele" @default.
- NCIT_C52355 NCIT_P96 "Cytochrome P450 2A6" @default.
- NCIT_C52355 NCIT_P98 "The poor metabolizer phenotype is characterized by the inability to use cytochrome P450-dependent metabolic pathways for drug elimination." @default.
- NCIT_C52355 NCIT_R130 NCIT_C18611 @default.
- NCIT_C52355 NCIT_R130 NCIT_C20633 @default.
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- NCIT_C52355 NCIT_R130 NCIT_C55290 @default.
- NCIT_C52355 NCIT_R130 NCIT_C91422 @default.
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- NCIT_C52355 NCIT_R130 NCIT_C91424 @default.
- NCIT_C52355 NCIT_R130 NCIT_C91437 @default.
- NCIT_C52355 NCIT_R37 NCIT_C16841 @default.
- NCIT_C52355 NCIT_R37 NCIT_C16945 @default.
- NCIT_C52355 NCIT_R37 NCIT_C17710 @default.
- NCIT_C52355 NCIT_R37 NCIT_C17828 @default.
- NCIT_C52355 NCIT_R37 NCIT_C18219 @default.
- NCIT_C52355 NCIT_R37 NCIT_C19390 @default.
- NCIT_C52355 NCIT_R37 NCIT_C19426 @default.
- NCIT_C52355 NCIT_R37 NCIT_C19536 @default.
- NCIT_C52355 NCIT_R37 NCIT_C19899 @default.
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- NCIT_C52355 NCIT_R40 NCIT_C12219 @default.
- NCIT_C52355 NCIT_R40 NCIT_C13282 @default.
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- NCIT_C52355 NCIT_R40 NCIT_C13432 @default.
- NCIT_C52355 NCIT_R40 NCIT_C13446 @default.
- NCIT_C52355 NCIT_R40 NCIT_C13655 @default.
- NCIT_C52355 NCIT_R40 NCIT_C14135 @default.
- NCIT_C52355 NCIT_R40 NCIT_C32221 @default.
- NCIT_C52355 NCIT_R40 NCIT_C34070 @default.
- NCIT_C52355 NCIT_R41 NCIT_C14182 @default.
- NCIT_C52355 NCIT_R41 NCIT_C14225 @default.
- NCIT_C52355 NCIT_R41 NCIT_C14234 @default.
- NCIT_C52355 NCIT_R41 NCIT_C14250 @default.
- NCIT_C52355 NCIT_R41 NCIT_C14262 @default.
- NCIT_C52355 NCIT_R41 NCIT_C14282 @default.
- NCIT_C52355 NCIT_R41 NCIT_C25796 @default.
- NCIT_C52355 NCIT_R41 NCIT_C79740 @default.
- NCIT_C52355 normalizedInformationContent "100" @default.
- NCIT_C52355 referenceCount "1" @default.
- NCIT_C52355 hasExactSynonym "CPA6" @default.
- NCIT_C52355 hasExactSynonym "CYP2A" @default.
- NCIT_C52355 hasExactSynonym "CYP2A3" @default.
- NCIT_C52355 hasExactSynonym "CYP2A6 wt Allele" @default.
- NCIT_C52355 hasExactSynonym "CYP2A6" @default.
- NCIT_C52355 hasExactSynonym "CYPIIA6" @default.
- NCIT_C52355 hasExactSynonym "Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 wt Allele" @default.
- NCIT_C52355 hasExactSynonym "Cytochrome P450, Subfamily IIA (Phenobarbital-Inducible), Polypeptide 6 Gene" @default.
- NCIT_C52355 hasExactSynonym "P450C2A" @default.
- NCIT_C52355 hasExactSynonym "P450PB" @default.
- NCIT_C52355 inSubset NCIT_C116977 @default.
- NCIT_C52355 inSubset NCIT_C142799 @default.
- NCIT_C52355 inSubset NCIT_C142800 @default.
- NCIT_C52355 type Class @default.
- NCIT_C52355 isDefinedBy ncit.owl @default.
- NCIT_C52355 label "CYP2A6 wt Allele" @default.
- NCIT_C52355 subClassOf NCIT_C16612 @default.
- NCIT_C52355 subClassOf NCIT_C21281 @default.
- NCIT_C52355 subClassOf NCIT_C25939 @default.
- NCIT_C52355 subClassOf NCIT_C26511 @default.
- NCIT_C52355 subClassOf NCIT_C48629 @default.
- NCIT_C52355 subClassOf NCIT_C52355 @default.
- NCIT_C52355 equivalentClass B048db152b27c2c4913d182aebc699b4b @default.
- NCIT_C52355 equivalentClass B4acc8d15569829c33588d0fba660be1e @default.