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• NCIT_C52519 IAO_0000115 "Human BCL6 wild-type allele is located in the vicinity of 3q27 and is approximately 24 kb in length. This allele, which encodes B-cell lymphoma 6 protein, is involved in the suppression of transcription. Various lymphoma and leukemia types are associated with aberrant forms of this gene." @default.
• NCIT_C52519 NCIT_NHC0 "C52519" @default.
• NCIT_C52519 NCIT_P100 "109565" @default.
• NCIT_C52519 NCIT_P102 "NM_138931" @default.
• NCIT_C52519 NCIT_P106 "Gene or Genome" @default.
• NCIT_C52519 NCIT_P107 "BCL6 wt Allele" @default.
• NCIT_C52519 NCIT_P108 "BCL6 wt Allele" @default.
• NCIT_C52519 NCIT_P207 "C1706239" @default.
• NCIT_C52519 NCIT_P211 "inflammatory response" @default.
• NCIT_C52519 NCIT_P211 "mediator complex" @default.
• NCIT_C52519 NCIT_P211 "negative regulation of transcription from Pol II promoter" @default.
• NCIT_C52519 NCIT_P211 "positive regulation of cell proliferation" @default.
• NCIT_C52519 NCIT_P211 "regulation of transcription, DNA-dependent" @default.
• NCIT_C52519 NCIT_P211 "transcription factor activity" @default.
• NCIT_C52519 NCIT_P321 "604" @default.
• NCIT_C52519 NCIT_P322 "CTRP" @default.
• NCIT_C52519 NCIT_P366 "BCL6_wt_Allele" @default.
• NCIT_C52519 NCIT_P96 "B-Cell Lymphoma 6 Protein" @default.
• NCIT_C52519 NCIT_P98 "The BCL6 gene is implicated in diffuse large B-cell lymphomas, which can be linked to either translocation t(3;7)(q27;p12), which fuses this gene with the IKZF1 gene, or translocation t(3;16)(q27;p11), which involves this gene and the IL21R gene. B-cell non-Hodgkin lymphoma is associated with at least three chromosomal rearrangements of the gene including t(3;6)(q27;p21), which fuses the BCL6 gene to the HIST1H4I gene, and both t(3;14)(q27;q32) and t(3;22)(q27;q11), which both embed the BCL6 gene in the immunoglobulin gene cluster. Some forms of B-cell leukemia are linked to translocation t(3;11)(q27;q23), which involves both the BCL6 gene and the POU2AF1 gene. Lymphoma has been associated with translocation t(3;4)(q27;p11), which fuses the BCL6 gene with the RHOH gene. (OMIM and SwissProt)" @default.
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