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NCIT_C53116 IAO_0000115 "Human RELA wild-type allele is located in the vicinity of 11q13 and is approximately 9 kb in length. This allele, which encodes transcription factor p65 protein, plays a role in the modulation of transcription by RNA polymerase II. Infrequently, lymphoproliferative disorders are associated with the translocation t(11;14)(q14;q32) of this gene. Amplification or increased expression of this gene has also been noted in some cases of squamous carcinomas of the head and neck and adenocarcinomas of the breast and stomach." @default.
NCIT_C53116 NCIT_NHC0 "C53116" @default.
NCIT_C53116 NCIT_P100 "164014" @default.
NCIT_C53116 NCIT_P102 "NM_021975" @default.
NCIT_C53116 NCIT_P106 "Gene or Genome" @default.
NCIT_C53116 NCIT_P107 "RELA wt Allele" @default.
NCIT_C53116 NCIT_P108 "RELA wt Allele" @default.
NCIT_C53116 NCIT_P207 "C1704704" @default.
NCIT_C53116 NCIT_P211 "anti-apoptosis" @default.
NCIT_C53116 NCIT_P211 "nucleus" @default.
NCIT_C53116 NCIT_P211 "protein binding" @default.
NCIT_C53116 NCIT_P211 "toxin resistance" @default.
NCIT_C53116 NCIT_P211 "transcription factor activity" @default.
NCIT_C53116 NCIT_P211 "transcription factor complex" @default.
NCIT_C53116 NCIT_P211 "transcription from Pol II promoter" @default.
NCIT_C53116 NCIT_P321 "5970" @default.
NCIT_C53116 NCIT_P322 "CTRP" @default.
NCIT_C53116 NCIT_P366 "RELA_wt_Allele" @default.
NCIT_C53116 NCIT_P96 "NF-Kappa B p65" @default.
NCIT_C53116 NCIT_P98 "The RELA gene product is a subunit of the nuclear factor kappa-B complex, a second messenger which activates the transcription of a number of genes in multiple tissues. The active form of the transcription factor p65 protein is a homodimer with nuclear factor kappa B polypeptides p50 or p52, which are capable of activating transcription in the nucleus. Under ordinary circumstances, p65 is found in the cytosol as a component of the nuclear factor kappa B protein complex associated with the inhibitory factor I kappa B. Activation releases the nuclear factor kappa B proteins from I kappa B and allows their nuclear import, resulting in transcriptional activation." @default.
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