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- NCIT_C53398 IAO_0000115 "A highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with potential antineoplastic activity. Dacomitinib specifically and irreversibly binds to and inhibits human Her-1, Her-2, and Her-4, resulting in the proliferation inhibition and apoptosis of tumor cells that overexpress these receptors." @default.
- NCIT_C53398 NCIT_A32 NCIT_C1909 @default.
- NCIT_C53398 NCIT_A7 NCIT_C17068 @default.
- NCIT_C53398 NCIT_NHC0 "C53398" @default.
- NCIT_C53398 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C53398 NCIT_P107 "Dacomitinib" @default.
- NCIT_C53398 NCIT_P108 "Dacomitinib" @default.
- NCIT_C53398 NCIT_P207 "C1709400" @default.
- NCIT_C53398 NCIT_P210 "1042385-75-0" @default.
- NCIT_C53398 NCIT_P302 "metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 L858R substitution mutations" @default.
- NCIT_C53398 NCIT_P319 "5092U85G58" @default.
- NCIT_C53398 NCIT_P322 "CTRP" @default.
- NCIT_C53398 NCIT_P322 "FDA" @default.
- NCIT_C53398 NCIT_P322 "GDC" @default.
- NCIT_C53398 NCIT_P325 "A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called protein tyrosine kinase inhibitors." @default.
- NCIT_C53398 NCIT_P329 "462567" @default.
- NCIT_C53398 NCIT_P330 "462567" @default.
- NCIT_C53398 NCIT_P350 "C24H25ClFN5O2.H2O" @default.
- NCIT_C53398 NCIT_P366 "PF-00299804" @default.
- NCIT_C53398 NCIT_P375 "Dacomitinib" @default.
- NCIT_C53398 NCIT_P399 "462567" @default.
- NCIT_C53398 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C53398 referenceCount "2" @default.
- NCIT_C53398 hasExactSynonym "(2E)-N-(4-((3-Chloro-4-Fluorophenyl)Amino)-7-Methoxyquinazolin-6-yl)-4-Piperidin-1-ylbut-2-Enamide" @default.
- NCIT_C53398 hasExactSynonym "DACOMITINIB" @default.
- NCIT_C53398 hasExactSynonym "Dacomitinib" @default.
- NCIT_C53398 hasExactSynonym "EGFR Inhibitor PF-00299804" @default.
- NCIT_C53398 hasExactSynonym "PF-00299804" @default.
- NCIT_C53398 hasExactSynonym "PF-00299804-03" @default.
- NCIT_C53398 hasExactSynonym "PF-299804" @default.
- NCIT_C53398 hasExactSynonym "Vizimpro" @default.
- NCIT_C53398 inSubset NCIT_C116977 @default.
- NCIT_C53398 inSubset NCIT_C116978 @default.
- NCIT_C53398 inSubset NCIT_C128784 @default.
- NCIT_C53398 inSubset NCIT_C157711 @default.
- NCIT_C53398 inSubset NCIT_C157712 @default.
- NCIT_C53398 inSubset NCIT_C176424 @default.
- NCIT_C53398 inSubset NCIT_C177537 @default.
- NCIT_C53398 inSubset NCIT_C63923 @default.
- NCIT_C53398 type Class @default.
- NCIT_C53398 isDefinedBy ncit.owl @default.
- NCIT_C53398 label "Dacomitinib" @default.
- NCIT_C53398 subClassOf NCIT_C129824 @default.
- NCIT_C53398 subClassOf NCIT_C129825 @default.
- NCIT_C53398 subClassOf NCIT_C1404 @default.
- NCIT_C53398 subClassOf NCIT_C163758 @default.
- NCIT_C53398 subClassOf NCIT_C163952 @default.
- NCIT_C53398 subClassOf NCIT_C1908 @default.
- NCIT_C53398 subClassOf NCIT_C1909 @default.
- NCIT_C53398 subClassOf NCIT_C1967 @default.
- NCIT_C53398 subClassOf NCIT_C2167 @default.
- NCIT_C53398 subClassOf NCIT_C2189 @default.
- NCIT_C53398 subClassOf NCIT_C274 @default.
- NCIT_C53398 subClassOf NCIT_C471 @default.
- NCIT_C53398 subClassOf NCIT_C53398 @default.